PAB1 proteasome subunit PAB1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PAB1
Official Full Name: proteasome subunit PAB1
Primary source: TAIR:AT1G16470
Locus tag: AT1G16470
See related: Araport:AT1G16470
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F3O9.27; F3O9_27; proteasome subunit PAB1
Summary: Encodes 20S proteasome subunit PAB1 (PAB1).
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Genomic context

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See PAB1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 11

Sequence:: Chromosome: 1; NC_003070.9 (5622746..5625683)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001035980.1

Supported by ESTs:

NM_101512.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to zinc ion	IEP Inferred from Expression Pattern more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed
located_in cytosolic ribosome	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
part_of proteasome complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome core complex	TAS Traceable Author Statement more info	PubMed
part_of proteasome core complex, alpha-subunit complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: proteasome subunit PAB1

NP_001031057.1

proteasome subunit PAB1 (PAB1); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: response to zinc ion, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex, cytosolic ribosome; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, alpha-subunit, conserved site (InterPro:IPR000426), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT1G79210.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_173096.1

proteasome subunit PAB1 (PAB1); FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: response to zinc ion, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex, cytosolic ribosome; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, alpha-subunit, conserved site (InterPro:IPR000426), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT1G79210.3); Has 6828 Blast hits to 6827 proteins in 505 species: Archae - 887; Bacteria - 62; Metazoa - 2417; Fungi - 1560; Plants - 881; Viruses - 0; Other Eukaryotes - 1021 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

5622746..5625683

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101512.4 → NP_173096.1 proteasome subunit PAB1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_173096.1

Status: REVIEWED

UniProtKB/Swiss-Prot

B9DGA9, O23708, Q94EI0

UniProtKB/TrEMBL

A0A178WA13, A0A5S9UQN6

Conserved Domains (1) summary

cd03750
Location:6 → 232

proteasome_alpha_type_2; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...
NM_001035980.1 → NP_001031057.1 proteasome subunit PAB1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001031057.1

Status: REVIEWED

UniProtKB/Swiss-Prot

B9DGA9, O23708, Q94EI0

UniProtKB/TrEMBL

A0A178WA13, A0A5S9UQN6

Conserved Domains (1) summary

cd03750
Location:6 → 232

proteasome_alpha_type_2; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...