NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001305134.2 → NP_001292063.1 tomoregulin-2 isoform 2 precursor
See identical proteins and their annotated locations for NP_001292063.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the 3' terminal exon and therefore differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AC098617, AF242222, AL157430
- Consensus CDS
-
CCDS82548.1
- UniProtKB/TrEMBL
-
B2RD22
- Related
- ENSP00000376128.1, ENST00000392314.5
- Conserved Domains (3) summary
-
- smart00280
Location:181 → 227
- KAZAL; Kazal type serine protease inhibitors
- cd00104
Location:95 → 135
- KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
- cl28647
Location:236 → 301
- PHA02887; EGF-like protein; Provisional
-
NM_001305145.1 → NP_001292074.1 tomoregulin-2 isoform 3 precursor
See identical proteins and their annotated locations for NP_001292074.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks several exons and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3, also known as TMEFF2-S) is shorter and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AC092644, AF242222, DQ133599
- Consensus CDS
-
CCDS82547.1
- UniProtKB/Swiss-Prot
-
Q9UIK5
- Related
- ENSP00000386871.3, ENST00000409056.3
- Conserved Domains (1) summary
-
- cd00104
Location:95 → 135
- KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
-
NM_016192.4 → NP_057276.2 tomoregulin-2 isoform 1 precursor
See identical proteins and their annotated locations for NP_057276.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC098617, AF179274, AF242222, AL157430
- Consensus CDS
-
CCDS2314.1
- UniProtKB/Swiss-Prot
- Q2FA44, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UIK5, Q9UK65
- UniProtKB/TrEMBL
- B2RD22, B3KQB7
- Related
- ENSP00000272771.5, ENST00000272771.10
- Conserved Domains (3) summary
-
- PHA02887
Location:236 → 301
- PHA02887; EGF-like protein; Provisional
- smart00280
Location:181 → 227
- KAZAL; Kazal type serine protease inhibitors
- cd00104
Location:95 → 135
- KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
191949046..192194933 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011510890.4 → XP_011509192.1 tomoregulin-2 isoform X1
See identical proteins and their annotated locations for XP_011509192.1
- UniProtKB/TrEMBL
- B2RD22, B3KQB7
- Conserved Domains (3) summary
-
- PHA02887
Location:227 → 292
- PHA02887; EGF-like protein; Provisional
- smart00280
Location:172 → 218
- KAZAL; Kazal type serine protease inhibitors
- cd00104
Location:95 → 135
- KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
-
XM_017003739.3 → XP_016859228.1 tomoregulin-2 isoform X2
- UniProtKB/TrEMBL
-
B2RD22
-
XM_017003740.3 → XP_016859229.1 tomoregulin-2 isoform X3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
192437261..192683624 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054341229.1 → XP_054197204.1 tomoregulin-2 isoform X1
- UniProtKB/TrEMBL
- B2RD22, B3KQB7
-
XM_054341230.1 → XP_054197205.1 tomoregulin-2 isoform X2
- UniProtKB/TrEMBL
-
B2RD22
-
XM_054341231.1 → XP_054197206.1 tomoregulin-2 isoform X3