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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029547.1 RefSeqGene
- Range
-
5001..49051
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000564.5 → NP_000555.2 interleukin-5 receptor subunit alpha isoform 1 precursor
See identical proteins and their annotated locations for NP_000555.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 4 both encode the same isoform (1).
- Source sequence(s)
-
AC022002, AC024060, AK304256, BX118481, DB222974, M96652, X61176
- Consensus CDS
-
CCDS2559.1
- UniProtKB/Swiss-Prot
- B3IU77, B4E2G0, Q01344, Q14633, Q15469, Q6ISX9
- UniProtKB/TrEMBL
-
Q14631
- Related
- ENSP00000256452.3, ENST00000256452.7
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_001243099.2 → NP_001230028.1 interleukin-5 receptor subunit alpha isoform 4 precursor
See identical proteins and their annotated locations for NP_001230028.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR and lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (4) has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AC022002, AC024060, AK304256, BX118481
- Consensus CDS
-
CCDS58813.1
- UniProtKB/TrEMBL
-
Q14631
- Related
- ENSP00000390753.1, ENST00000438560.5
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_175724.2 → NP_783851.1 interleukin-5 receptor subunit alpha isoform 2 precursor
See identical proteins and their annotated locations for NP_783851.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' end region, which leads to a translation frameshift, when compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, as compared to isoform 1.
- Source sequence(s)
-
AC024060, BI520196, DB229011, M96651, X62156
- Consensus CDS
-
CCDS46739.1
- UniProtKB/TrEMBL
-
Q8NHV7
- Related
- ENSP00000400400.2, ENST00000430514.6
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_175725.3 → NP_783852.1 interleukin-5 receptor subunit alpha isoform 3 precursor
See identical proteins and their annotated locations for NP_783852.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 3' end region, which leads to a translation frameshift, when compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, as compared to isoform 1.
- Source sequence(s)
-
AC024060, BI520196, DB229011, M75914, X62156
- Consensus CDS
-
CCDS2560.1
- UniProtKB/TrEMBL
-
Q8NHV7
- Related
- ENSP00000309196.8, ENST00000311981.12
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_175726.4 → NP_783853.1 interleukin-5 receptor subunit alpha isoform 1 precursor
See identical proteins and their annotated locations for NP_783853.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an internal segment within the 5' UTR, as compared to variant 1. Variants 1 and 4 encode the same isoform (1).
- Source sequence(s)
-
AC022002, AK304256, BX118481, DB222974, M96652, X61176
- Consensus CDS
-
CCDS2559.1
- UniProtKB/Swiss-Prot
- B3IU77, B4E2G0, Q01344, Q14633, Q15469, Q6ISX9
- UniProtKB/TrEMBL
-
Q14631
- Related
- ENSP00000412209.2, ENST00000446632.7
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_175727.2 → NP_783854.1 interleukin-5 receptor subunit alpha isoform 2 precursor
See identical proteins and their annotated locations for NP_783854.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an internal segment within the 5' UTR, and differs in the 3' end region, when compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, as compared to isoform 1.
- Source sequence(s)
-
BI520196, DB229011, M96651, X62156
- Consensus CDS
-
CCDS46739.1
- UniProtKB/TrEMBL
-
Q8NHV7
- Related
- ENSP00000392059.1, ENST00000456302.5
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_175728.3 → NP_783855.1 interleukin-5 receptor subunit alpha isoform 3 precursor
See identical proteins and their annotated locations for NP_783855.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks an internal segment within the 5' UTR, and differs in the 3' end region, when compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, as compared to isoform 1.
- Source sequence(s)
-
BC027599, BI520196, DB229011, M75914, X62156
- Consensus CDS
-
CCDS2560.1
- UniProtKB/TrEMBL
-
Q8NHV7
- Related
- ENSP00000373358.1, ENST00000383846.5
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
3066324..3110374 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011533677.2 → XP_011531979.1 interleukin-5 receptor subunit alpha isoform X1
See identical proteins and their annotated locations for XP_011531979.1
- UniProtKB/TrEMBL
-
Q14631
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
XM_011533678.3 → XP_011531980.1 interleukin-5 receptor subunit alpha isoform X1
See identical proteins and their annotated locations for XP_011531980.1
- UniProtKB/TrEMBL
-
Q14631
- Conserved Domains (2) summary
-
- pfam09240
Location:129 → 236
- IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
- cl21522
Location:25 → 107
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
3060643..3104729 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054346456.1 → XP_054202431.1 interleukin-5 receptor subunit alpha isoform X1
- UniProtKB/TrEMBL
-
Q14631
-
XM_054346455.1 → XP_054202430.1 interleukin-5 receptor subunit alpha isoform X1
- UniProtKB/TrEMBL
-
Q14631