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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029885.1 RefSeqGene
- Range
-
5022..71586
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001135213.3 → NP_001128685.1 ARF GTPase-activating protein GIT2 isoform 6
See identical proteins and their annotated locations for NP_001128685.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks two in-frame exons in the 3' coding region and includes an additional short in-frame exon in the central coding region, compared to isoform 1. The resulting isoform (6) is missing two internal fragments and includes a 2 residue insertion, compared to isoform 1.
- Source sequence(s)
-
AA813937, BP871813, D63482
- Consensus CDS
-
CCDS55884.1
- UniProtKB/TrEMBL
-
R4GNG3
- Related
- ENSP00000391813.2, ENST00000457474.6
- Conserved Domains (5) summary
-
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
- cd08847
Location:1 → 111
- ArfGap_GIT2; GIT2 GTPase activating protein for Arf
- pfam08518
Location:268 → 296
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:563 → 674
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
-
NM_001135214.3 → NP_001128686.1 ARF GTPase-activating protein GIT2 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks one in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (5) is missing one fragment but has the same N- and C-termini as isoform 1.
- Source sequence(s)
-
AA813937, AF124491, BP871813, CR749340, D63482
- Consensus CDS
-
CCDS44968.1
- UniProtKB/TrEMBL
-
R4GNG3
- Related
- ENSP00000354282.5, ENST00000361006.9
- Conserved Domains (7) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:608 → 722
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 478
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
NM_001330153.2 → NP_001317082.1 ARF GTPase-activating protein GIT2 isoform 7
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) uses an alternate in-frame splice site and lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting isoform (7) is shorter but has the same N- and C-termini as isoform 1.
- Source sequence(s)
-
AA813937, AF124491, BE646544, BP871813, CR980157, D63482
- Consensus CDS
-
CCDS81736.1
- UniProtKB/TrEMBL
- F8VXI9, R4GNG3
- Related
- ENSP00000448832.1, ENST00000551209.5
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:265 → 293
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:587 → 701
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
NM_001330154.2 → NP_001317083.1 ARF GTPase-activating protein GIT2 isoform 8
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) lacks most 3' exons and has an alternate exon at the 3' end, as compared to variant 1. Isoform 8 is much shorter and has a different C-terminus than isoform 1.
- Source sequence(s)
-
AC084876, AK222736, BM557270, BP871813
- Consensus CDS
-
CCDS81737.1
- UniProtKB/TrEMBL
- B4E2E7, F8W822
- Related
- ENSP00000323833.9, ENST00000320063.10
- Conserved Domains (4) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
- pfam08518
Location:266 → 293
- GIT_SHD; Spa2 homology domain (SHD) of GIT
-
NM_014776.5 → NP_055591.2 ARF GTPase-activating protein GIT2 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks two exons in the coding region, as compared to variant 1. Isoform 3 is missing two fragments but has the same N- and C-termini as isoform 1.
- Source sequence(s)
-
AA813937, AF124491, BP871813, D63482
- UniProtKB/TrEMBL
-
R4GNG3
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:558 → 672
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
NM_057169.5 → NP_476510.1 ARF GTPase-activating protein GIT2 isoform 1
See identical proteins and their annotated locations for NP_476510.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AA813937, AF124491, BP871813, D63482
- Consensus CDS
-
CCDS9138.1
- UniProtKB/Swiss-Prot
- Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2
- UniProtKB/TrEMBL
-
R4GNG3
- Related
- ENSP00000347464.3, ENST00000355312.8
- Conserved Domains (7) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:638 → 752
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 478
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
NM_057170.5 → NP_476511.1 ARF GTPase-activating protein GIT2 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks two exons and a portion of a third exon in the coding region, as compared to variant 1. The reading frame is maintained. Isoform 2 is missing internal 128 aa but has the same N- and C-termini as isoform 1.
- Source sequence(s)
-
AA813937, AK308304, BC014223, BP871813, D63482
- Consensus CDS
-
CCDS44969.1
- UniProtKB/TrEMBL
-
R4GNG3
- Related
- ENSP00000447465.1, ENST00000553118.5
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
- pfam08518
Location:266 → 293
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:510 → 624
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam16559
Location:414 → 450
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
-
NM_139201.3 → NP_631940.2 ARF GTPase-activating protein GIT2 isoform 4
See identical proteins and their annotated locations for NP_631940.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks most 3' exons and has an alternate exon at the 3' end, as compared to variant 1. Isoform 4 is much shorter and has a different C-terminus than isoform 1.
- Source sequence(s)
-
AC084876, AK222736, BM557270, BP871813
- Consensus CDS
-
CCDS9139.1
- UniProtKB/TrEMBL
- B5BU58, Q6FI58
- Related
- ENSP00000450348.1, ENST00000547815.5
- Conserved Domains (6) summary
-
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
- cd08847
Location:1 → 111
- ArfGap_GIT2; GIT2 GTPase activating protein for Arf
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 465
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- pfam14203
Location:246 → 284
- TTRAP; Putative tranposon-transfer assisting protein
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
109929804..110000164 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047429924.1 → XP_047285880.1 ARF GTPase-activating protein GIT2 isoform X8
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_047429926.1 → XP_047285882.1 ARF GTPase-activating protein GIT2 isoform X10
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_047429925.1 → XP_047285881.1 ARF GTPase-activating protein GIT2 isoform X9
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_017020258.3 → XP_016875747.1 ARF GTPase-activating protein GIT2 isoform X6
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_047429922.1 → XP_047285878.1 ARF GTPase-activating protein GIT2 isoform X3
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_047429923.1 → XP_047285879.1 ARF GTPase-activating protein GIT2 isoform X4
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_005253997.5 → XP_005254054.1 ARF GTPase-activating protein GIT2 isoform X1
- UniProtKB/TrEMBL
-
R4GNG3
- Conserved Domains (7) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:265 → 293
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:637 → 751
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:413 → 477
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
XM_006719712.5 → XP_006719775.1 ARF GTPase-activating protein GIT2 isoform X11
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:475 → 589
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
XM_006719709.5 → XP_006719772.1 ARF GTPase-activating protein GIT2 isoform X7
- UniProtKB/TrEMBL
-
R4GNG3
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:588 → 702
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
XM_006719708.5 → XP_006719771.1 ARF GTPase-activating protein GIT2 isoform X5
- UniProtKB/TrEMBL
-
R4GNG3
- Conserved Domains (7) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:593 → 707
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 463
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
XM_006719707.5 → XP_006719770.1 ARF GTPase-activating protein GIT2 isoform X2
- UniProtKB/TrEMBL
-
R4GNG3
- Conserved Domains (7) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12205
Location:623 → 737
- GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 463
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
-
XM_047429928.1 → XP_047285884.1 ARF GTPase-activating protein GIT2 isoform X15
- UniProtKB/TrEMBL
-
B4E2E7
-
XM_047429927.1 → XP_047285883.1 ARF GTPase-activating protein GIT2 isoform X14
- UniProtKB/TrEMBL
-
B5BU58
-
XM_017020261.3 → XP_016875750.1 ARF GTPase-activating protein GIT2 isoform X12
- UniProtKB/TrEMBL
-
B5BU58
-
XM_006719713.5 → XP_006719776.1 ARF GTPase-activating protein GIT2 isoform X13
- UniProtKB/TrEMBL
-
B5BU58
- Conserved Domains (6) summary
-
- smart00105
Location:2 → 124
- ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
- cd00204
Location:109 → 220
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam08518
Location:266 → 294
- GIT_SHD; Spa2 homology domain (SHD) of GIT
- pfam12796
Location:137 → 229
- Ank_2; Ankyrin repeats (3 copies)
- pfam16559
Location:414 → 449
- GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
- sd00045
Location:137 → 165
- ANK; ANK repeat [structural motif]
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
109905496..109975853 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054373915.1 → XP_054229890.1 ARF GTPase-activating protein GIT2 isoform X8
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373917.1 → XP_054229892.1 ARF GTPase-activating protein GIT2 isoform X10
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373916.1 → XP_054229891.1 ARF GTPase-activating protein GIT2 isoform X9
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373913.1 → XP_054229888.1 ARF GTPase-activating protein GIT2 isoform X6
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373910.1 → XP_054229885.1 ARF GTPase-activating protein GIT2 isoform X3
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373911.1 → XP_054229886.1 ARF GTPase-activating protein GIT2 isoform X4
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373908.1 → XP_054229883.1 ARF GTPase-activating protein GIT2 isoform X1
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373918.1 → XP_054229893.1 ARF GTPase-activating protein GIT2 isoform X11
-
XM_054373914.1 → XP_054229889.1 ARF GTPase-activating protein GIT2 isoform X7
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373912.1 → XP_054229887.1 ARF GTPase-activating protein GIT2 isoform X5
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373909.1 → XP_054229884.1 ARF GTPase-activating protein GIT2 isoform X2
- UniProtKB/TrEMBL
-
R4GNG3
-
XM_054373922.1 → XP_054229897.1 ARF GTPase-activating protein GIT2 isoform X15
- UniProtKB/TrEMBL
-
B4E2E7
-
XM_054373921.1 → XP_054229896.1 ARF GTPase-activating protein GIT2 isoform X14
- UniProtKB/TrEMBL
-
B5BU58
-
XM_054373919.1 → XP_054229894.1 ARF GTPase-activating protein GIT2 isoform X12
- UniProtKB/TrEMBL
-
B5BU58
-
XM_054373920.1 → XP_054229895.1 ARF GTPase-activating protein GIT2 isoform X13
- UniProtKB/TrEMBL
-
B5BU58