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    CG7218 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42165, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7218provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038569
    Locus tag
    Dmel_CG7218
    See related
    AllianceGenome:FB:FBgn0038569
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7218
    Summary
    Predicted to be involved in positive regulation of cilium assembly. Predicted to be active in ciliary basal body and endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human TAPT1 (transmembrane anterior posterior transformation 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7218 in Genome Data Viewer
    Location:
    90F4-90F4; 3-62 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18161392..18164397, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13987114..13990119, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45103 Neighboring gene antisense RNA:CR45104 Neighboring gene uncharacterized protein Neighboring gene cap binding protein 20 Neighboring gene uncharacterized protein Neighboring gene Peroxiredoxin 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    2. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7218-PA
    CG7218-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18161392..18164397 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300456.1 → NP_001287385.1  uncharacterized protein Dmel_CG7218, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287385.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VED0
      UniProtKB/TrEMBL
      A0A0B4LH99
      Conserved Domains (1) summary
      pfam05346
      Location:166 → 470
      DUF747; Eukaryotic membrane protein family

    2. NM_142421.4 → NP_650678.1  uncharacterized protein Dmel_CG7218, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650678.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VED0
      UniProtKB/TrEMBL
      A0A0B4LH99
      Related
      FBpp0083043
      Conserved Domains (1) summary
      pfam05346
      Location:166 → 470
      DUF747; Eukaryotic membrane protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LH99 A0A0B4LH99
    Q9VED0.2 Q9VED0

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