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    CG15130 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15130provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032860
    Locus tag
    Dmel_CG15130
    See related
    AllianceGenome:FB:FBgn0032860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38C.48; Dmel\CG15130
    Summary
    Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 6 and sensorineural hearing loss. Orthologous to human TMIE (transmembrane inner ear). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15130 in Genome Data Viewer
    Location:
    38C6-38C6; 2-54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20423106..20424660, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20423106..20424660, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Actin-related protein 2/3 complex, subunit 2 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43607 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Map position and expression of the genes in the 38 region of Drosophila. Butler H, et al. Genetics, 2001 Aug. PMID 11514449, Free PMC Article
    2. Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing. Sutton DC, et al. PLoS One, 2024. PMID 38412189, Free PMC Article
    3. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article
    4. Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila. Meltzer H, et al. Nat Commun, 2019 May 8. PMID 31068592, Free PMC Article
    5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15130-PB
    CG15130-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20423106..20424660 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136190.3 → NP_610034.2  uncharacterized protein Dmel_CG15130, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610034.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIM4
      Conserved Domains (1) summary
      pfam16038
      Location:13 → 97
      TMIE; TMIE protein

    2. NM_001259175.2 → NP_001246104.1  uncharacterized protein Dmel_CG15130, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246104.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NEV1
      Conserved Domains (1) summary
      pfam16038
      Location:13 → 94
      TMIE; TMIE protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NEV1 M9NEV1
    Q9VIM4 Q9VIM4

    Gene LinkOut

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