Madm MLF1-adaptor molecule [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Madmprovided by FlyBase
Official Full Name: MLF1-adaptor moleculeprovided by FlyBase
Primary source: FLYBASE:FBgn0027497
Locus tag: Dmel_CG1098
See related: AllianceGenome:FB:FBgn0027497
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.406; BcDNA:LD28657; CG1098; dMADM; Dmel\CG1098; lincRNA.S6031; MadM; MADM
Summary: Predicted to enable protein homodimerization activity. Involved in several processes, including intestinal stem cell homeostasis; protein secretion; and regulation of cell size. Located in Golgi apparatus and cytosol. Is expressed in cyst progenitor cell; organism; and somatic cell of testis. Orthologous to human NRBP1 (nuclear receptor binding protein 1) and NRBP2 (nuclear receptor binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (5742510..5747138)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (1568232..1572584)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
NOT enables protein kinase activity	IKR Inferred from Key Residues more info	PubMed

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in intestinal stem cell homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in protein secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of cell size	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in endomembrane system	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain