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    Acsx3 Acyl-CoA synthetase X3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42354, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Acsx3provided by FlyBase
    Official Full Name
    Acyl-CoA synthetase X3provided by FlyBase
    Primary source
    FLYBASE:FBgn0038733
    Locus tag
    Dmel_CG11407
    See related
    AllianceGenome:FB:FBgn0038733
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11407; Dmel\CG11407
    Summary
    Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. Is expressed in adult head and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Acsx3 in Genome Data Viewer
    Location:
    92B2-92B2; 3-67 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19781246..19783145)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15606968..15608867)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Acyl-CoA synthetase X1 R Neighboring gene Acyl-CoA synthetase X2 Neighboring gene Acyl-CoA synthetase X4 Neighboring gene transfer RNA:Valine-CAC 2-6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A tandem duplication in Drosophila melanogaster shows enhanced expression beyond the gene copy number. Loehlin DW, et al. Genetics, 2022 Mar 3. PMID 35100388, Free PMC Article
    2. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Inouye S. Cell Mol Life Sci, 2010 Feb. PMID 19859663, Free PMC Article
    3. Characterization of CG6178 gene product with high sequence similarity to firefly luciferase in Drosophila melanogaster. Oba Y, et al. Gene, 2004 Mar 31. PMID 15033536
    4. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. Oba Y, et al. Biosci Biotechnol Biochem, 2005 Apr. PMID 15849423
    5. Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor. Rand MD, et al. Toxicol Sci, 2008 Jul. PMID 18367466

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables long-chain fatty acid-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty-acyl-CoA biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in long-chain fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Acyl-CoA synthetase X3
    Names
    Acsx3-PA
    CG11407-PA
    NP_650831.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19781246..19783145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142574.3 → NP_650831.1  Acyl-CoA synthetase X3 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDU1
      Related
      FBpp0083204
      Conserved Domains (2) summary
      cd05911
      Location:47 → 522
      Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)
      COG0318
      Location:26 → 523
      CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDU1 Q9VDU1

    Gene LinkOut

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