Rnf11 Ring finger protein 11 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rnf11provided by FlyBase
Official Full Name: Ring finger protein 11provided by FlyBase
Primary source: FLYBASE:FBgn0052850
Locus tag: Dmel_CG32850
See related: AllianceGenome:FB:FBgn0052850
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE41137; BEST:GH26713; CG32850; Dmel\CG32850; dRNF11; RNF-11; RNF11
Summary: Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Acts upstream of with a negative effect on regulation of dopamine secretion. Predicted to be part of ubiquitin ligase complex. Is expressed in adult head and larval central nervous system. Orthologous to human RNF11 (ring finger protein 11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	4	NC_004353.4 (314923..331387)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	4	NC_004353.3 (335549..352013)

Chromosome 4 - NC_004353.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Ring Finger Protein 11 (RNF11) Modulates Dopamine Release in Drosophila.
Title: Ring Finger Protein 11 (RNF11) Modulates Dopamine Release in Drosophila.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	ISS Inferred from Sequence or Structural Similarity more info
enables ubiquitin-protein transferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables zinc ion binding	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in protein autoubiquitination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_negative_effect regulation of dopamine secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ubiquitin ligase complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain