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    Ir52c Ionotropic receptor 52c [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246630, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ir52cprovided by FlyBase
    Official Full Name
    Ionotropic receptor 52cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050468
    Locus tag
    Dmel_CG30468
    See related
    AllianceGenome:FB:FBgn0050468
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    52c; CG12961; CG30468; DmelIR52c; Dmel\CG30468; IR52c
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Involved in reproductive behavior. Predicted to be located in membrane. Is expressed in appendage; leg taste bristle chemosensory neurons; prothoracic tarsal bristle; and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir52c in Genome Data Viewer
    Location:
    52A6-52A6; 2-74 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15504201..15506000)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11391706..11393505)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 52a Neighboring gene Ionotropic receptor 52b Neighboring gene Ionotropic receptor 52d Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pheromone processing in Drosophila. Kohl J, et al. Curr Opin Neurobiol, 2015 Oct. PMID 26143522, Free PMC Article
    2. Molecular basis of fatty acid taste in Drosophila. Ahn JE, et al. Elife, 2017 Dec 12. PMID 29231818, Free PMC Article
    3. Sexual circuitry in Drosophila. Auer TO, et al. Curr Opin Neurobiol, 2016 Jun. PMID 26851712
    4. Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. Stotz SC, et al. PLoS One, 2012. PMID 23056495, Free PMC Article
    5. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in reproductive behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 52c
    Names
    CG30468-PA
    Ir52c-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15504201..15506000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166098.1 → NP_725470.1  ionotropic receptor 52c [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725470.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A077D9S7, A1ZA16
      Related
      FBpp0086462, FBtr0087329
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZA16 A1ZA16

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