ND-20L NADH dehydrogenase (ubiquinone) 20 kDa subunit-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ND-20Lprovided by FlyBase
Official Full Name: NADH dehydrogenase (ubiquinone) 20 kDa subunit-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0039669
Locus tag: Dmel_CG2014
See related: AllianceGenome:FB:FBgn0039669
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG2014; Dmel\CG2014; dNDUFS7B; ND20-like; NUKM
Summary: Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Involved in inter-male aggressive behavior. Part of respiratory chain complex I. Is expressed in adult head. Human ortholog(s) of this gene implicated in developmental disorder of mental health and nuclear type mitochondrial complex I deficiency 3. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (29515717..29516527)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (25341439..25342249)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase (ubiquinone) activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info
contributes_to NADH dehydrogenase activity	ISS Inferred from Sequence or Structural Similarity more info
enables quinone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in aerobic respiration	IBA Inferred from Biological aspect of Ancestor more info
involved_in electron transport coupled proton transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in inter-male aggressive behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial respiratory chain complex I assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IC Inferred by Curator more info	PubMed
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

Names: CG2014-PA; CG2014-PB; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH: ubiquinone oxidoreductase-like, 20kDa subunit; NADH:ubiquinone oxidoreductase 20 kDa subunit; ND-20L-PA; ND-20L-PB

NP_001287584.1

NP_651698.1

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The following sections contain reference sequences that belong to a specific genome build. Explain