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    hng2 hinge2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41056, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hng2provided by FlyBase
    Official Full Name
    hinge2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037634
    Locus tag
    Dmel_CG8359
    See related
    AllianceGenome:FB:FBgn0037634
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8359; Dmel\CG8359
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including antennal primordium; central brain primordium; ganglia; head epidermis primordium; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See hng2 in Genome Data Viewer
    Location:
    85B2-85B2; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8806322..8807581)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4632044..4633303)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene PFTAIRE-interacting factor 1B Neighboring gene PFTAIRE-interacting factor 1A Neighboring gene Ionotropic receptor 85a Neighboring gene Chaperonin containing TCP1 subunit 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43130 Neighboring gene aaquetzalli

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
    2. Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge. Shukla V, et al. Genetics, 2014 Feb. PMID 24336749, Free PMC Article
    3. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article
    4. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article
    5. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hinge2
    Names
    CG8359-PA
    hng2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8806322..8807581
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141580.3 → NP_649837.1  hinge2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649837.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHL0
      Related
      FBpp0081402
      Conserved Domains (2) summary
      pfam02944
      Location:216 → 250
      BESS; BESS motif
      pfam10545
      Location:21 → 113
      MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHL0 Q9VHL0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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