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    CG8204 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36728, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8204provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034033
    Locus tag
    Dmel_CG8204
    See related
    AllianceGenome:FB:FBgn0034033
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT23078; Dmel\CG8204
    Summary
    Predicted to be involved in box C/D snoRNP assembly; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and snoRNA localization. Predicted to be part of pre-snoRNP complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in PEHO syndrome. Orthologous to human ZNHIT3 (zinc finger HIT-type containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8204 in Genome Data Viewer
    Location:
    52A13-52A13; 2-74 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15573144..15573991, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11460649..11461496, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Flotillin 1 Neighboring gene Cyclin-dependent kinase 5 Neighboring gene uncharacterized protein Neighboring gene mir-278 stem loop Neighboring gene fusilli Neighboring gene antisense RNA:CR45143

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila cdk5 is needed for locomotive behavior and NMJ elaboration, but seems dispensable for synaptic transmission. Kissler AE, et al. Dev Neurobiol, 2009 May. PMID 19263480
    2. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407
    3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in box C/D snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in snoRNA localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of pre-snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8204-PA
    CG8204-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15573144..15573991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137206.3 → NP_611050.1  uncharacterized protein Dmel_CG8204, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611050.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZA28, Q8T407
      Related
      FBpp0086482
      Conserved Domains (1) summary
      pfam04438
      Location:1 → 30
      zf-HIT; HIT zinc finger

    2. NM_001299535.1 → NP_001286464.1  uncharacterized protein Dmel_CG8204, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286464.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZA28, Q8T407
      Conserved Domains (1) summary
      pfam04438
      Location:1 → 30
      zf-HIT; HIT zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZA28 A1ZA28
    Q8T407 Q8T407

    Gene LinkOut

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