Lamtor5 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Lamtor5provided by FlyBase
Official Full Name: Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5provided by FlyBase
Primary source: FLYBASE:FBgn0026090
Locus tag: Dmel_CG14812
See related: AllianceGenome:FB:FBgn0026090
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE59545; CG14812; dHBXIP; Dmel\CG14812; EG:131F2.3; HBXIP
Summary: Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in cellular response to amino acid stimulus and positive regulation of TORC1 signaling. Predicted to be located in cytoplasm. Predicted to be part of Ragulator complex. Predicted to be active in lysosome. Is expressed in adult head. Orthologous to human LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (1857889..1858971, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (1751922..1753004, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to guanyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cellular response to amino acid stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to amino acid stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cysteine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of TORC1 signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of TORC1 signaling	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Ragulator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Ragulator complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in lysosome	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

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The following sections contain reference sequences that belong to a specific genome build. Explain