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    Gs1l GS1-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33653, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gs1lprovided by FlyBase
    Official Full Name
    GS1-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0019982
    Locus tag
    Dmel_CG15441
    See related
    AllianceGenome:FB:FBgn0019982
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    19864674; CG15441; Dmel\CG15441; gs1-like; GS1l
    Summary
    Predicted to enable pseudouridine 5'-phosphatase activity. Involved in wound healing. Is expressed in adult head. Orthologous to human PUDP (pseudouridine 5'-phosphatase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Gs1l in Genome Data Viewer
    Location:
    24F3-24F3; 2-12 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4455137..4456807, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4455137..4456807, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA Selenocysteine associated protein Neighboring gene NADH dehydrogenase (ubiquinone) B8 subunit Neighboring gene ncRNA Neighboring gene Ribosomal protein L27A Neighboring gene mitochondrial ribosomal protein L27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and sequencing of ribosomal protein L27a and a gene similar to human GS1 in Drosophila. Soehnge H, et al. Gene, 1997 Feb 7. PMID 9055824
    2. Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies. Santarelli S, et al. Front Neurosci, 2023. PMID 37274187, Free PMC Article
    3. Comparison of larval and adult Drosophila astrocytes reveals stage-specific gene expression profiles. Huang Y, et al. G3 (Bethesda), 2015 Feb 4. PMID 25653313, Free PMC Article
    4. Buffering of Genetic Regulatory Networks in Drosophila melanogaster. Fear JM, et al. Genetics, 2016 Jul. PMID 27194752, Free PMC Article
    5. Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Campos I, et al. Genetics, 2010 Jan. PMID 19884309, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine 5'-phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in wound healing HMP PubMed 

    General protein information

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    Preferred Names
    GS1-like
    Names
    CG15441-PA
    CG15441-PB
    GS1-like protein
    GS1like
    Gs1l-PA
    Gs1l-PB
    NP_477228.1
    NP_477229.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4455137..4456807 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057881.5 → NP_477229.3  GS1-like, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477229.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2QCN9
      Conserved Domains (2) summary
      COG0637
      Location:12 → 220
      YcjU; Beta-phosphoglucomutase or related phosphatase, HAD superfamily [Carbohydrate transport and metabolism, General function prediction only]
      cl21460
      Location:16 → 231
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    2. NM_057880.5 → NP_477228.1  GS1-like, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477228.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02536, Q494L7, Q94529, Q9VR01
      Related
      FBpp0077143
      Conserved Domains (2) summary
      COG0637
      Location:12 → 220
      YcjU; Beta-phosphoglucomutase or related phosphatase, HAD superfamily [Carbohydrate transport and metabolism, General function prediction only]
      cl21460
      Location:16 → 231
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E2QCN9 E2QCN9
    Q94529.2 Q94529

    Gene LinkOut

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