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    CG3408 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39107, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3408provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036008
    Locus tag
    Dmel_CG3408
    See related
    AllianceGenome:FB:FBgn0036008
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT11439; Dmel\CG3408
    Summary
    Predicted to be active in cytoplasm. Is expressed in several structures, including CNS glial cell; adult head; central brain primordium; embryonic central brain neurons; and ganglia. Orthologous to human LRRC59 (leucine rich repeat containing 59). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3408 in Genome Data Viewer
    Location:
    67B10-67B11; 3-29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9506818..9509583, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9499918..9502683, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pathetic Neighboring gene ncRNA Neighboring gene antisense RNA:CR45874 Neighboring gene Ribosomal protein S9 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Single-nucleus RNA-sequencing in pre-cellularization Drosophila melanogaster embryos. Albright AR, et al. PLoS One, 2022. PMID 35749552, Free PMC Article
    2. Expression profiling of glial genes during Drosophila embryogenesis. Altenhein B, et al. Dev Biol, 2006 Aug 15. PMID 16762338
    3. Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription. Saunders A, et al. Genes Dev, 2013 May 15. PMID 23699410, Free PMC Article
    4. Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model. Voutyraki C, et al. Proc Natl Acad Sci U S A, 2023 Aug 15. PMID 37549261, Free PMC Article
    5. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial nucleoid ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3408-PA
    CG3408-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9506818..9509583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274706.1 → NP_001261635.1  uncharacterized protein Dmel_CG3408, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261635.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEX7
      Conserved Domains (3) summary
      cd00116
      Location:39 → 120
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:40 → 62
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:61 → 119
      LRR_8; Leucine rich repeat

    2. NM_140071.4 → NP_648328.1  uncharacterized protein Dmel_CG3408, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648328.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VT05
      Related
      FBpp0076155
      Conserved Domains (3) summary
      cd00116
      Location:43 → 124
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:44 → 66
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:65 → 123
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEX7 M9PEX7
    Q9VT05 Q9VT05

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