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    Cad89D Cadherin 89D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42006, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cad89Dprovided by FlyBase
    Official Full Name
    Cadherin 89Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038439
    Locus tag
    Dmel_CG14900
    See related
    AllianceGenome:FB:FBgn0038439
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14900; CT34724; DCad89D; Dmel\CG14900
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules and cell-cell adhesion mediated by cadherin. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cad89D in Genome Data Viewer
    Location:
    89B18-89B18; 3-58 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16484566..16495422, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12310288..12321144, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Dihydrofolate reductase Neighboring gene Succinate dehydrogenase assembly factor 3 Neighboring gene Derlin-2 Neighboring gene Gustatory receptor 89a Neighboring gene Death executioner caspase related to Apopain/Yama

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cadherins in embryonic and neural morphogenesis. Tepass U, et al. Nat Rev Mol Cell Biol, 2000 Nov. PMID 11253370
    2. Expression patterns of cadherin genes in Drosophila oogenesis. Zartman JJ, et al. Gene Expr Patterns, 2009 Jan. PMID 18817893, Free PMC Article
    3. Expression profile of the cadherin family in the developing Drosophila brain. Fung S, et al. J Comp Neurol, 2008 Jan 20. PMID 18041774
    4. Cadherin superfamily proteins in Caenorhabditis elegans and Drosophila melanogaster. Hill E, et al. J Mol Biol, 2001 Feb 2. PMID 11162110
    5. Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose. Ji Z, et al. Elife, 2021 Apr 13. PMID 33847264, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion mediated by cadherin ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cadherin 89D
    Names
    CG14900-PB
    Cad89D-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16484566..16495422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142297.4 → NP_650554.3  cadherin 89D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650554.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NR53, Q9GR86, Q9VEU1
      Conserved Domains (2) summary
      cd11304
      Location:1289 → 1385
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:1026 → 1085
      CA; Cadherin repeats
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VEU1.3 Q9VEU1

    Gene LinkOut

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