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    CG10359 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38434, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10359provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035452
    Locus tag
    Dmel_CG10359
    See related
    AllianceGenome:FB:FBgn0035452
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AAF47782; Dmel\CG10359; FBpp0072995
    Summary
    Predicted to enable G protein-coupled receptor binding activity and chitin binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including dorsal head epidermis; embryonic hypopharynx; embryonic salivary gland duct; ganglia; and larval glial cell. Orthologous to human TNR (tenascin R). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10359 in Genome Data Viewer
    Location:
    63E5-63E5; 3-8 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3612192..3615244)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3612192..3615244)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ecdysone-induced protein 63E Neighboring gene long non-coding RNA:CR45820 Neighboring gene small nuclear RNA U7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of embryonic expression within multigene families using the FlyExpress discovery platform reveals more spatial than temporal divergence. Konikoff CE, et al. Dev Dyn, 2012 Jan. PMID 21960044, Free PMC Article
    2. Dying cells protect survivors from radiation-induced cell death in Drosophila. Bilak A, et al. PLoS Genet, 2014 Mar. PMID 24675716, Free PMC Article
    3. Identification and characterization of the fibrinogen-like domain of fibrinogen-related proteins in the mosquito, Anopheles gambiae, and the fruitfly, Drosophila melanogaster, genomes. Wang X, et al. BMC Genomics, 2005 Sep 8. PMID 16150145, Free PMC Article
    4. Evolution and potential function of fibrinogen-like domains across twelve Drosophila species. Middha S, et al. BMC Genomics, 2008 May 30. PMID 18513432, Free PMC Article
    5. Microarray analysis of replicate populations selected against a wing-shape correlation in Drosophila melanogaster. Weber KE, et al. Genetics, 2008 Feb. PMID 18245369, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables chitin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10359-PE
    CG10359-PG
    Fibrinogen-related protein
    Fibronogen-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3612192..3615244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144410.2 → NP_001137882.1  uncharacterized protein Dmel_CG10359, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137882.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0B2, Q8SYI4, Q9VZN7
      Conserved Domains (1) summary
      cd00087
      Location:267 → 476
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

    2. NM_001144409.2 → NP_001137881.1  uncharacterized protein Dmel_CG10359, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137881.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0B3, Q8SYI4, Q9VZN7
      Conserved Domains (1) summary
      cd00087
      Location:241 → 450
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z0B2 B7Z0B2
    B7Z0B3 B7Z0B3
    Q95S38 Q95S38
    Q9VZN7 Q9VZN7

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