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    janB janus B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43568, updated on 9-Dec-2024

    Summary

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    Official Symbol
    janBprovided by FlyBase
    Official Full Name
    janus Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0001281
    Locus tag
    Dmel_CG7931
    See related
    AllianceGenome:FB:FBgn0001281
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs30f02.y1; CG31024; CG7931; Dmel\CG7931; jan; Jan; jan B; Jan-B; janus
    Summary
    Predicted to enable protein histidine phosphatase activity. Involved in sex differentiation. Predicted to be active in cytosol. Is expressed in organism; spermatocyte; spermatozoon; and testis. Orthologous to human PHPT1 (phosphohistidine phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See janB in Genome Data Viewer
    Location:
    99D3-99D3; 3-100 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30037984..30038728, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25863706..25864450, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Axin Neighboring gene Zinc-finger protein interacting with CP190 Neighboring gene ocnus Neighboring gene Serendipity alpha Neighboring gene Serendipity beta Neighboring gene janus A Neighboring gene Serendipity delta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. X chromosome inactivation during Drosophila spermatogenesis. Hense W, et al. PLoS Biol, 2007 Oct. PMID 17927450, Free PMC Article
    2. Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. Parsch J, et al. Genetics, 2001 Oct. PMID 11606541, Free PMC Article
    3. Translational control in spermatogenesis. Schäfer M, et al. Dev Biol, 1995 Dec. PMID 8612956
    4. Sequence and structure of the serendipity locus of Drosophila melanogaster. A densely transcribed region including a blastoderm-specific gene. Vincent A, et al. J Mol Biol, 1985 Nov 5. PMID 3935797
    5. Single amino acid exchanges in separate domains of the Drosophila serendipity delta zinc finger protein cause embryonic and sex biased lethality. Crozatier M, et al. Genetics, 1992 Aug. PMID 1516821, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein histidine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in sex differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    janus B
    Names
    CG7931-PA
    janB-PA
    janus
    janusB
    NP_476584.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30037984..30038728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057236.5 → NP_476584.2  janus B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476584.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0ANH4, A0ANH5, A0ANH6, A0ANH7, A0ANH8, A0ANI2, P20349, Q9VAB7
      UniProtKB/TrEMBL
      C0MHU3, C0MHU7
      Related
      FBpp0084963
      Conserved Domains (1) summary
      pfam05005
      Location:31 → 128
      Ocnus; Janus/Ocnus family (Ocnus)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20349.1 P20349

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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