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    Cbln3 cerebellin 3 precursor protein [ Mus musculus (house mouse) ]

    Gene ID: 56410, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cbln3provided by MGI
    Official Full Name
    cerebellin 3 precursor proteinprovided by MGI
    Primary source
    MGI:MGI:1889286
    See related
    Ensembl:ENSMUSG00000040380 AllianceGenome:MGI:1889286
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in maintenance of synapse structure. Located in extracellular space and synapse. Is active in parallel fiber to Purkinje cell synapse and synaptic cleft. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human CBLN3 (cerebellin 3 precursor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward cerebellum adult (RPKM 133.2) See more
    Orthologs
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    Genomic context

    See Cbln3 in Genome Data Viewer
    Location:
    14 C3; 14 28.19 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (56116377..56121713, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (55878920..55884256, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 Neighboring gene STARR-seq mESC enhancer starr_36783 Neighboring gene NYN domain and retroviral integrase containing Neighboring gene STARR-positive B cell enhancer ABC_E7318 Neighboring gene STARR-positive B cell enhancer ABC_E7319 Neighboring gene KH and NYN domain containing Neighboring gene short chain dehydrogenase/reductase family 39U, member 1 Neighboring gene STARR-seq mESC enhancer starr_36786 Neighboring gene chymase 1, mast cell

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in maintenance of synapse structure IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    is_active_in parallel fiber to Purkinje cell synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic cleft IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cerebellin-3
    Names
    precerebellin 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019820.3NP_062794.1  cerebellin-3 precursor

      See identical proteins and their annotated locations for NP_062794.1

      Status: PROVISIONAL

      Source sequence(s)
      AC098877
      Consensus CDS
      CCDS27133.1
      UniProtKB/Swiss-Prot
      Q9JHG0
      Related
      ENSMUSP00000070494.6, ENSMUST00000063871.13
      Conserved Domains (1) summary
      cl23878
      Location:63197
      C1q; C1q domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      56116377..56121713 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)