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    Mettl9 methyltransferase like 9 [ Mus musculus (house mouse) ]

    Gene ID: 59052, updated on 3-Dec-2024

    Summary

    Official Symbol
    Mettl9provided by MGI
    Official Full Name
    methyltransferase like 9provided by MGI
    Primary source
    MGI:MGI:1914862
    See related
    Ensembl:ENSMUSG00000030876 AllianceGenome:MGI:1914862
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drev; mMETTL9; MNCb-5680; 0610012D09Rik
    Summary
    Enables protein-L-histidine N-pros-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in mitochondrion. Predicted to be active in endoplasmic reticulum. Is expressed in retina inner nuclear layer and retina outer nuclear layer. Orthologous to human METTL9 (methyltransferase 9, His-X-His N1(pi)-histidine). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 36.9), CNS E14 (RPKM 28.6) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mettl9 in Genome Data Viewer
    Location:
    7 F2; 7 65.07 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (120631717..120676058)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121032384..121076835)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 13B Neighboring gene STARR-positive B cell enhancer ABC_E4973 Neighboring gene predicted pseudogene 9234 Neighboring gene predicted gene, 25924 Neighboring gene predicted gene, 27991 Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene immunoglobulin superfamily, member 6 Neighboring gene otoancorin Neighboring gene STARR-seq mESC enhancer starr_20059 Neighboring gene src family associated phosphoprotein 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein-L-histidine N-pros-methyltransferase
    Names
    DORA reverse strand protein
    methyltransferase-like protein 9
    NP_001405493.1
    NP_001405494.1
    NP_001405495.1
    NP_001405496.1
    NP_001405497.1
    NP_001405498.1
    NP_001405499.1
    NP_001405500.1
    NP_001405501.1
    NP_001405502.1
    NP_001405503.1
    NP_001405504.1
    NP_001405505.1
    NP_001405506.1
    NP_001405507.1
    NP_001405508.1
    NP_001405509.1
    NP_001405510.1
    NP_001405511.1
    NP_001405512.1
    NP_067529.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418564.1NP_001405493.1  protein-L-histidine N-pros-methyltransferase isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC140782
    2. NM_001418565.1NP_001405494.1  protein-L-histidine N-pros-methyltransferase isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC140782
    3. NM_001418566.1NP_001405495.1  protein-L-histidine N-pros-methyltransferase isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC140782
    4. NM_001418567.1NP_001405496.1  protein-L-histidine N-pros-methyltransferase isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    5. NM_001418568.1NP_001405497.1  protein-L-histidine N-pros-methyltransferase isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC140782
    6. NM_001418569.1NP_001405498.1  protein-L-histidine N-pros-methyltransferase isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC140782
    7. NM_001418570.1NP_001405499.1  protein-L-histidine N-pros-methyltransferase isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC140782
    8. NM_001418571.1NP_001405500.1  protein-L-histidine N-pros-methyltransferase isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    9. NM_001418572.1NP_001405501.1  protein-L-histidine N-pros-methyltransferase isoform 10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC140782
    10. NM_001418573.1NP_001405502.1  protein-L-histidine N-pros-methyltransferase isoform 11 precursor

      Status: VALIDATED

      Source sequence(s)
      AC140782
    11. NM_001418574.1NP_001405503.1  protein-L-histidine N-pros-methyltransferase isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    12. NM_001418575.1NP_001405504.1  protein-L-histidine N-pros-methyltransferase isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    13. NM_001418576.1NP_001405505.1  protein-L-histidine N-pros-methyltransferase isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
      Related
      ENSMUSP00000147071.2, ENSMUST00000207351.2
    14. NM_001418577.1NP_001405506.1  protein-L-histidine N-pros-methyltransferase isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    15. NM_001418578.1NP_001405507.1  protein-L-histidine N-pros-methyltransferase isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    16. NM_001418579.1NP_001405508.1  protein-L-histidine N-pros-methyltransferase isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC140782
      UniProtKB/TrEMBL
      A0A140LJ45
    17. NM_001418580.1NP_001405509.1  protein-L-histidine N-pros-methyltransferase isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC140782
    18. NM_001418581.1NP_001405510.1  protein-L-histidine N-pros-methyltransferase isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC140782
    19. NM_001418582.1NP_001405511.1  protein-L-histidine N-pros-methyltransferase isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC140782
    20. NM_001418583.1NP_001405512.1  protein-L-histidine N-pros-methyltransferase isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC140782
    21. NM_021554.3NP_067529.2  protein-L-histidine N-pros-methyltransferase isoform 1 precursor

      See identical proteins and their annotated locations for NP_067529.2

      Status: VALIDATED

      Source sequence(s)
      AC140782
      Consensus CDS
      CCDS21800.1
      UniProtKB/Swiss-Prot
      A0JG25, Q3TDX0, Q641L4, Q8R567, Q9EPL3, Q9EPL4, Q9JJ88
      Related
      ENSMUSP00000033163.7, ENSMUST00000033163.8
      Conserved Domains (1) summary
      pfam05219
      Location:56317
      DREV; DREV methyltransferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      120631717..120676058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)