Rpl7l1 ribosomal protein L7-like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpl7l1provided by MGI
Official Full Name: ribosomal protein L7-like 1provided by MGI
Primary source: MGI:MGI:1913479
See related: Ensembl:ENSMUSG00000063888 AllianceGenome:MGI:1913479
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1500016H10Rik
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within blastocyst formation. Located in nucleolus. Is expressed in several structures, including brain; integumental system; pancreas; reproductive system; and retina. Orthologous to human RPL7L1 (ribosomal protein L7 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 27.1), liver E14 (RPKM 24.2) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 17 22.9 cM; 17 C

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (47084833..47093582, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (46773907..46782656, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Rpl7l1 is required for the blastocyst formation.
Title: Identification of four genes required for mammalian blastocyst formation.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blastocyst formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	TAS Traceable Author Statement more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: large ribosomal subunit protein uL30-like 1

Names: 60S ribosomal protein L7-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_025433.3 → NP_079709.2 large ribosomal subunit protein uL30-like 1

See identical proteins and their annotated locations for NP_079709.2

Status: PROVISIONAL

Source sequence(s)

CT030702

Consensus CDS

CCDS28842.1

UniProtKB/Swiss-Prot

Q9D8M4

UniProtKB/TrEMBL

Q3U8B9

Related

ENSMUSP00000092888.5, ENSMUST00000078286.6

Conserved Domains (3) summary

cd01657
Location:87 → 246

Ribosomal_L7_archeal_euk; Ribosomal protein L7, which is found in archaea and eukaryotes but not in prokaryotes, binds domain II of the 23S rRNA as well as the 5S rRNA and is one of five ribosomal proteins that mediate the interactions 5S rRNA makes with the ribosome. The ...

TIGR01310
Location:15 → 246

uL30_euk; 60S ribosomal protein uL30, eukaryotic form

pfam08079
Location:16 → 85

Ribosomal_L30_N; Ribosomal L30 N-terminal domain