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    VPS45 vacuolar protein sorting 45 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844050, updated on 18-Sep-2024

    Summary

    Official Symbol
    VPS45
    Official Full Name
    vacuolar protein sorting 45
    Primary source
    TAIR:AT1G77140
    Locus tag
    AT1G77140
    See related
    Araport:AT1G77140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATVPS45; BEN2; bfa-visualized endocytic trafficking defective 2; T14N5.2; T14N5_2; vacuolar protein sorting 45
    Summary
    A peripheral membrane protein that associates with microsomal membranes, likely to function in the transport of proteins to the vacuole. It is a member of Sec1p protein family. It may be involved in the regulation of vesicle fusion reactions through interaction with t-SNAREs at the Golgi trans face.
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    Genomic context

    See VPS45 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (28983934..28988035)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene plant glycogenin-like starch initiation protein 2 Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene transmembrane protein, putative (DUF506) Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_106364.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
     
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network NAS
    Non-traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    vacuolar protein sorting 45
    NP_565150.1
    • vacuolar protein sorting 45 (VPS45); CONTAINS InterPro DOMAIN/s: Sec1-like protein (InterPro:IPR001619); BEST Arabidopsis thaliana protein match is: secretory 1A (TAIR:AT1G02010.1); Has 1795 Blast hits to 1777 proteins in 228 species: Archae - 0; Bacteria - 2; Metazoa - 694; Fungi - 525; Plants - 216; Viruses - 0; Other Eukaryotes - 358 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28983934..28988035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106364.2NP_565150.1  vacuolar protein sorting 45 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565150.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49048, O80650
      UniProtKB/TrEMBL
      A0A178WPE4, A0A5S9WV28
      Conserved Domains (1) summary
      pfam00995
      Location:22548
      Sec1; Sec1 family