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    GPT2 glucose-6-phosphate/phosphate translocator 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842477, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPT2
    Official Full Name
    glucose-6-phosphate/phosphate translocator 2
    Primary source
    TAIR:AT1G61800
    Locus tag
    AT1G61800
    See related
    Araport:AT1G61800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS GLUCOSE-6-PHOSPHATE/PHOSPHATE TRANSLOCATOR 2; ATGPT2; glucose-6-phosphate/phosphate translocator 2; GLUCOSE6-PHOSPHATE/PHOSPHATE TRANSPORTER 2; T13M11.18; T13M11_18
    Summary
    glucose6-Phosphate/phosphate transporter 2. Expression is upregulated in the shoot of cax1/cax3 mutant.
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    Genomic context

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    See GPT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (22824414..22826902)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Oligosaccharyltransferase complex/magnesium transporter family protein Neighboring gene PAK-box/P21-Rho-binding family protein Neighboring gene beta-glucosidase 45 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chloroplasts Are Central Players in Sugar-Induced Leaf Growth. Van Dingenen J, et al. Plant Physiol, 2016 May. PMID 26932234, Free PMC Article
    2. Acclimation of metabolism to light in Arabidopsis thaliana: the glucose 6-phosphate/phosphate translocator GPT2 directs metabolic acclimation. Dyson BC, et al. Plant Cell Environ, 2015 Jul. PMID 25474495, Free PMC Article
    3. The role of plastidial glucose-6-phosphate/phosphate translocators in vegetative tissues of Arabidopsis thaliana mutants impaired in starch biosynthesis. Kunz HH, et al. Plant Biol (Stuttg), 2010 Sep. PMID 20712627
    4. Dynamic acclimation of photosynthesis increases plant fitness in changing environments. Athanasiou K, et al. Plant Physiol, 2010 Jan. PMID 19939944, Free PMC Article
    5. The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development. Niewiadomski P, et al. Plant Cell, 2005 Mar. PMID 15722468, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GPT2 plays a critical role in the sucrose-mediated effects on early leaf growth.
      Title: Chloroplasts Are Central Players in Sugar-Induced Leaf Growth.
    2. GPT2 alters the distribution of metabolites between compartments and that this plays an essential role in allowing the cell to interpret environmental signals.
      Title: Acclimation of metabolism to light in Arabidopsis thaliana: the glucose 6-phosphate/phosphate translocator GPT2 directs metabolic acclimation.
    3. GPT2 contributes significantly to the measurable Glc6P transport activity in leaves of mutants impaired in starch biosynthesis. A knockout of GPT2 in the background of adg1-1 additionally impairs growth under short-day conditions.
      Title: The role of plastidial glucose-6-phosphate/phosphate translocators in vegetative tissues of Arabidopsis thaliana mutants impaired in starch biosynthesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001334001.1
    NM_104862.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glucose-6-phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoglycerate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables triose-phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in glucose-6-phosphate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoglycerate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within photosynthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in photosynthetic acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of photosynthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to glucose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to sucrose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in triose phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    glucose-6-phosphate/phosphate translocator 2
    NP_564785.1
    • glucose-6-phosphate/phosphate translocator 2 (GPT2); FUNCTIONS IN: antiporter activity, glucose-6-phosphate transmembrane transporter activity; INVOLVED IN: in 7 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Tpt phosphate/phosphoenolpyruvate translocator (InterPro:IPR004696), Protein of unknown function DUF250 (InterPro:IPR004853); BEST Arabidopsis thaliana protein match is: glucose 6-phosphate/phosphate translocator 1 (TAIR:AT5G54800.1); Has 2231 Blast hits to 2230 proteins in 287 species: Archae - 2; Bacteria - 36; Metazoa - 463; Fungi - 366; Plants - 1109; Viruses - 0; Other Eukaryotes - 255 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22824414..22826902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104862.4 → NP_564785.1  glucose-6-phosphate/phosphate translocator 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564785.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80688, Q94B38
      UniProtKB/TrEMBL
      A0A5S9WNG5
      Conserved Domains (2) summary
      TIGR00817
      Location:95 → 387
      tpt; Tpt phosphate/phosphoenolpyruvate translocator
      pfam00892
      Location:105 → 228
      EamA; EamA-like transporter family

    2. NM_001334001.1 → NP_001320539.1  glucose-6-phosphate/phosphate translocator 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AN56, A0A5S9WNG5
      Conserved Domains (1) summary
      TIGR00817
      Location:95 → 389
      tpt; Tpt phosphate/phosphoenolpyruvate translocator
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94B38.2

    Gene LinkOut

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