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    EMB2763 ribonuclease II family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816257, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2763
    Official Full Name
    ribonuclease II family protein
    Primary source
    TAIR:AT2G17510
    Locus tag
    AT2G17510
    See related
    Araport:AT2G17510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRRP44A; EMBRYO DEFECTIVE 2763; MJB20.7; MJB20_7; Rrp44 homolog A; RRP44A
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    Genomic context

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    See EMB2763 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    25
    Sequence:
    Chromosome: 2; NC_003071.7 (7609236..7616342, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Auxin efflux carrier family protein Neighboring gene Endoribonuclease/protein kinase IRE1-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis AtRRP44A is the functional homolog of Rrp44/Dis3, an exosome component, is essential for viability and is required for RNA processing and degradation. Kumakura N, et al. PLoS One, 2013. PMID 24244451, Free PMC Article
    2. An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata. Kitagawa M, et al. Science, 2022 Jan 14. PMID 35025667
    3. The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana. Lange H, et al. PLoS Genet, 2014 Aug. PMID 25144737, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata.
      Title: An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata.
    2. These results indicate that AtRRP44A and AtRRP44B/SOV have independent roles for RNA turnover in plants.
      Title: Arabidopsis AtRRP44A is the functional homolog of Rrp44/Dis3, an exosome component, is essential for viability and is required for RNA processing and degradation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001202612.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribonuclease II family protein
    NP_001189541.1
    • EMBRYO DEFECTIVE 2763 (EMB2763); FUNCTIONS IN: ribonuclease activity, RNA binding; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide binding protein, PINc (InterPro:IPR006596), Ribonuclease II/R (InterPro:IPR001900); BEST Arabidopsis thaliana protein match is: Ribonuclease II/R family protein (TAIR:AT1G77680.1).
    NP_565418.1
    • EMBRYO DEFECTIVE 2763 (EMB2763); FUNCTIONS IN: ribonuclease activity, RNA binding; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide binding protein, PINc (InterPro:IPR006596), Ribonuclease II/R (InterPro:IPR001900); BEST Arabidopsis thaliana protein match is: Ribonuclease II/R family protein (TAIR:AT1G77680.1); Has 8124 Blast hits to 8011 proteins in 2302 species: Archae - 41; Bacteria - 5304; Metazoa - 409; Fungi - 408; Plants - 147; Viruses - 2; Other Eukaryotes - 1813 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7609236..7616342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127305.3 → NP_565418.1  ribonuclease II family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565418.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZK2, Q9SHL7
      UniProtKB/TrEMBL
      A0A5S9WYQ9, A0A654ETM4
      Conserved Domains (2) summary
      COG0557
      Location:236 → 933
      VacB; Exoribonuclease R [Transcription]
      cd09862
      Location:9 → 178
      PIN_Rrp44-like; VapC-like PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

    2. NM_001202612.1 → NP_001189541.1  ribonuclease II family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189541.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WYQ9, A0A654ETM4, F4INI6
      Conserved Domains (3) summary
      cd09862
      Location:54 → 223
      PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs
      TIGR02063
      Location:281 → 1012
      RNase_R; ribonuclease R
      pfam00773
      Location:536 → 877
      RNB; RNB domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SHL7.2

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