ECH2 enoyl-CoA hydratase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ECH2
Official Full Name: enoyl-CoA hydratase 2
Primary source: TAIR:AT1G76150
Locus tag: AT1G76150
See related: Araport:AT1G76150
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATECH2; enoyl-CoA hydratase 2; T23E18.9; T23E18_9
Summary: Encodes a monofunctional enoyl-CoA hydratase 2, involved in the degradation of even cis-unsaturated fatty acids, gene expression is enhanced during the first 2 days of germination, as well as in senescent leaves.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

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ECH2 is required for IBA responsiveness
Title: Multiple facets of Arabidopsis seedling development require indole-3-butyric acid-derived auxin.
AtECH2 encodes a monofunctional peroxisomal enoyl-CoA hydratase 2 that participates in vivo in the conversion of the intermediate 3R-hydroxyacyl-CoA, generated by the metabolism of fatty acids to 2E-enoyl-CoA for further degradation. [AtECH2]
Title: Identification and functional characterization of a monofunctional peroxisomal enoyl-CoA hydratase 2 that participates in the degradation of even cis-unsaturated fatty acids in Arabidopsis thaliana.

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NM_106264.3

Function	Evidence Code	Pubs
enables 3-hydroxyacyl-CoA dehydratase activity	IDA Inferred from Direct Assay more info	PubMed
enables 3-hydroxyacyl-CoA dehydratase activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid beta-oxidation, unsaturated, even number	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in peroxisome	HDA more info	PubMed
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed

NP_177742.2

enoyl-CoA hydratase 2 (ECH2); FUNCTIONS IN: oxidoreductase activity, 3R-hydroxyacyl-CoA dehydratase activity; INVOLVED IN: fatty acid beta-oxidation, unsaturated, even number, metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: MaoC-like dehydratase (InterPro:IPR002539), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); Has 2242 Blast hits to 2242 proteins in 541 species: Archae - 23; Bacteria - 1245; Metazoa - 172; Fungi - 395; Plants - 47; Viruses - 0; Other Eukaryotes - 360 (source: NCBI BLink).