U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CENP-C centromere protein C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838135, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CENP-C
    Official Full Name
    centromere protein C
    Primary source
    TAIR:AT1G15660
    Locus tag
    AT1G15660
    See related
    Araport:AT1G15660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CENP-C HOMOLOGUE; centromere protein C; T16N11.16; T16N11_16
    Summary
    Encodes a homologue of the human centromeric protein C (CENP-C). CENP-C co-localizes with the 180 bp centromeric regions of chromosomes throughout the cell cycle, but does not completely cover the 180 bp regions.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CENP-C in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (5381032..5385380)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA-Ser Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Characterization of a CENP-C homolog in Arabidopsis thaliana. Ogura Y, et al. Genes Genet Syst, 2004 Jun. PMID 15329494
    2. Differential localization of the centromere-specific proteins in the major centromeric satellite of Arabidopsis thaliana. Shibata F, et al. J Cell Sci, 2004 Jun 15. PMID 15161939
    3. Targeting of Arabidopsis KNL2 to Centromeres Depends on the Conserved CENPC-k Motif in Its C Terminus. Sandmann M, et al. Plant Cell, 2017 Jan. PMID 28062749, Free PMC Article
    4. Arabidopsis MZT1 homologs GIP1 and GIP2 are essential for centromere architecture. Batzenschlager M, et al. Proc Natl Acad Sci U S A, 2015 Jul 14. PMID 26124146, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that KINETOCHORE NULL2 (KNL2) recognizes centromeric nucleosomes, similar to centromere protein C (CENP-C), via the CENPC-k motif and binds adjoining DNA.
      Title: Targeting of Arabidopsis KNL2 to Centromeres Depends on the Conserved CENPC-k Motif in Its C Terminus.
    2. CENP-C is present at the centromeric regions throughout the cell cycle.[CENP-C]
      Title: Characterization of a CENP-C homolog in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_101434.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables centromeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in kinetochore assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    centromere protein C
    NP_173018.2
    • centromere protein C (CENP-C); Has 380 Blast hits to 353 proteins in 129 species: Archae - 0; Bacteria - 6; Metazoa - 108; Fungi - 26; Plants - 78; Viruses - 8; Other Eukaryotes - 154 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5381032..5385380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101434.4 → NP_173018.2  centromere protein C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173018.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q66LG9, Q68BI6, Q68BI7, Q9M9D0
      UniProtKB/TrEMBL
      A0A5S9UJC8, A0A654EB65
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66LG9.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.