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    NHL8 NDR1/HIN1-like 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840126, updated on 18-Sep-2024

    Summary

    Official Symbol
    NHL8
    Official Full Name
    NDR1/HIN1-like 8
    Primary source
    TAIR:AT1G32340
    Locus tag
    AT1G32340
    See related
    Araport:AT1G32340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F27G20.5; NDR1/HIN1-like 8
    Summary
    Encodes a protein whose sequence is similar to tobacco hairpin-induced gene (HIN1) and Arabidopsis non-race specific disease resistance gene (NDR1). Expression is not detected under normal conditions and in response to cucumber mosaic virus or spermine.
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    Genomic context

    See NHL8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (11663008..11666120, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor A1D Neighboring gene uncharacterized protein Neighboring gene alternative oxidase 1D Neighboring gene miscRNA

    General gene information

    NM_102967.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    NDR1/HIN1-like 8
    NP_174512.1
    • NDR1/HIN1-like 8 (NHL8); FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, C6HC-type (InterPro:IPR002867), Zinc finger, RING-type (InterPro:IPR001841), RWD (InterPro:IPR006575); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT3G14250.1); Has 3653 Blast hits to 3199 proteins in 223 species: Archae - 0; Bacteria - 0; Metazoa - 1736; Fungi - 604; Plants - 670; Viruses - 7; Other Eukaryotes - 636 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11663008..11666120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102967.3NP_174512.1  NDR1/HIN1-like 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174512.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W2B0, Q9LQM5
      Conserved Domains (4) summary
      smart00591
      Location:192323
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
      smart00647
      Location:446504
      IBR; In Between Ring fingers
      pfam01485
      Location:527582
      IBR; IBR domain, a half RING-finger domain
      cl17238
      Location:376427
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain