MPK9 MAP kinase 9 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MPK9
Official Full Name: MAP kinase 9
Primary source: TAIR:AT3G18040
Locus tag: AT3G18040
See related: Araport:AT3G18040
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MAP kinase 9
Summary: Encodes a protein with similarity to MAP kinases (MAPK9).Expressed preferentially in guard cells and appears to be involved in reactive oxygen species mediated ABA signaling.
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Genomic context

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See MPK9 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 12

Sequence:: Chromosome: 3; NC_003074.8 (6174239..6178534)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MPK9 and MPK12 are positive regulators of salicylic acid signaling in Arabidopsis guard cells.
Title: MPK9 and MPK12 function in SA-induced stomatal closure in Arabidopsis thaliana.
MPK9 and MPK12 are key regulators mediating both abscisic acid (ABA) and Methyl jasmonate (MeJA) signalling in guard cells.
Title: Two guard cell mitogen-activated protein kinases, MPK9 and MPK12, function in methyl jasmonate-induced stomatal closure in Arabidopsis thaliana.
Data suggest that MPK9 is autoactivated via phosphorylation independent of any upstream MAPK kinase signaling; autophosphorylation occurs at both threonine and tyrosine residues in Thr-Asp-Tyr motif and in C-terminal regulatory extension.
Title: Activation of AtMPK9 through autophosphorylation that makes it independent of the canonical MAPK cascades.
MPK9 and MPK12 function redundantly downstream of extracellular reactive oxygen production and intracellular accumulation, cytosolic alkalisation and Ca(2+)cytosolic oscillation in yeast elcictor-induced stomatal closure
Title: Two guard cell-preferential MAPKs, MPK9 and MPK12, regulate YEL signalling in Arabidopsis guard cells.
MPK9 and MPK12 act downstream of ROS and cytosolic Ca2+ and upstream of anion channels in the guard cell abscisic acid signaling cascade.
Title: Two Arabidopsis guard cell-preferential MAPK genes, MPK9 and MPK12, function in biotic stress response.
MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling.
Title: MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001338321.1

Supported by ESTs:

NM_112686.4

Supported by ESTs:

NM_202602.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables MAP kinase activity	IEA Inferred from Electronic Annotation more info
enables MAP kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within signal transduction	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: MAP kinase 9

NP_566595.1

MAP kinase 9 (MPK9); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: MAP kinase 15 (TAIR:AT1G73670.1); Has 122703 Blast hits to 121413 proteins in 4361 species: Archae - 122; Bacteria - 13975; Metazoa - 45582; Fungi - 12439; Plants - 29950; Viruses - 578; Other Eukaryotes - 20057 (source: NCBI BLink).

NP_974331.1

MAP kinase 9 (MPK9); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAP kinase 15 (TAIR:AT1G73670.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

6174239..6178534

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001338320.1 → NP_001327298.1 MAP kinase 9 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRW2, A0A654F8B2
NM_001338319.1 → NP_001327296.1 MAP kinase 9 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRW0, A0A654F8B2
NM_112686.4 → NP_566595.1 MAP kinase 9 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566595.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LV37, Q9MB22

UniProtKB/TrEMBL

A0A7G2EQ25

Conserved Domains (2) summary

cd07859
Location:22 → 359

STKc_TDY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TDY Mitogen-Activated Protein Kinases

smart00220
Location:23 → 314

S_TKc; Serine/Threonine protein kinases, catalytic domain
NM_001338321.1 → NP_001327297.1 MAP kinase 9 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRW1, A0A7G2EQ25
NM_202602.2 → NP_974331.1 MAP kinase 9 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_974331.1

Status: REVIEWED

UniProtKB/TrEMBL

F4J7I7

Conserved Domains (2) summary

smart00220
Location:11 → 226

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl21453
Location:1 → 271

PKc_like; Protein Kinases, catalytic domain