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    ESM1 GDSL-like lipase/acylhydrolase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820639, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ESM1
    Official Full Name
    GDSL-like lipase/acylhydrolase superfamily protein
    Primary source
    TAIR:AT3G14210
    Locus tag
    AT3G14210
    See related
    Araport:AT3G14210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    epithiospecifier modifier 1
    Summary
    A semidominant QTL which has an epistatic effect on the Epithiospecifier gene. Represses nitrile formation and favors isothiocyanate production during glucosinolate hydrolysis. The functional allele deters the insect herbivory T. ni.
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    Genomic context

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    See ESM1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (4729399..4731847)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Phosphoinositide phosphatase family protein Neighboring gene ncRNA Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene GDSL-motif lipase 4 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ESP and ESM1 mediate indol-3-acetonitrile production from indol-3-ylmethyl glucosinolate in Arabidopsis. Burow M, et al. Phytochemistry, 2008 Feb. PMID 17920088
    2. The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis. Zhang Z, et al. Plant Cell, 2006 Jun. PMID 16679459, Free PMC Article
    3. Identification of Interactions between Abscisic Acid and Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase. Galka MM, et al. PLoS One, 2015. PMID 26197050, Free PMC Article
    4. Purification of low-abundance Arabidopsis plasma-membrane protein complexes and identification of candidate components. Qi Y, et al. Plant J, 2009 Mar. PMID 19000159
    5. Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. Reumann S, et al. Plant Cell, 2007 Oct. PMID 17951448, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Epithiospecifier modifier 1 gene controlled to produce significant levels of indol-3-acetonitrile formation.
      Title: ESP and ESM1 mediate indol-3-acetonitrile production from indol-3-ylmethyl glucosinolate in Arabidopsis.
    2. EPITHIOSPECIFIER MODIFIER1 (ESM1) epistatically represses nitrile formation and favors isothiocyanate production in combination with ESP. The glucosinolate hydrolysis profile change influenced by ESM1 is associated with insect resistance[ESM1]
      Title: The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001338114.1
    NM_112278.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucosinolate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to insect IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in peroxisome HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    GDSL-like lipase/acylhydrolase superfamily protein
    NP_188037.1
    • epithiospecifier modifier 1 (ESM1); FUNCTIONS IN: hydrolase activity, acting on ester bonds, carboxylesterase activity; INVOLVED IN: glucosinolate catabolic process, response to cold, defense response to bacterium, response to insect; LOCATED IN: in 8 components; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: myrosinase-associated protein, putative (TAIR:AT1G54010.1); Has 1512 Blast hits to 1501 proteins in 69 species: Archae - 0; Bacteria - 44; Metazoa - 1; Fungi - 2; Plants - 1464; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4729399..4731847
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112278.3 → NP_188037.1  GDSL-like lipase/acylhydrolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188037.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MAV7, Q941A3, Q9LJG3
      UniProtKB/TrEMBL
      A0A178V7Z2
      Conserved Domains (1) summary
      cd01837
      Location:36 → 344
      SGNH_plant_lipase_like; SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all ...

    2. NM_001338114.1 → NP_001326872.1  GDSL-like lipase/acylhydrolase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LQL1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJG3.1

    Gene LinkOut

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