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    DGK1 diacylglycerol kinase1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830686, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DGK1
    Official Full Name
    diacylglycerol kinase1
    Primary source
    TAIR:AT5G07920
    Locus tag
    AT5G07920
    See related
    Araport:AT5G07920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATDGK1; DIACYLGLYCEROL KINASE 1; diacylglycerol kinase1; F13G24.120; F13G24_120
    Summary
    diacylglycerol kinase
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    Genomic context

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    See DGK1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (2524687..2529421, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Mitochondrial transcription termination factor family protein Neighboring gene ncRNA Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene MEI2 C-terminal RRM only like 2 Neighboring gene dentin sialophosphoprotein-like protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of a cDNA encoding diacylglycerol kinase (DGK) in Arabidopsis thaliana. Katagiri T, et al. Plant Mol Biol, 1996 Feb. PMID 8605313
    2. The hydrophobic segment of Arabidopsis thaliana cluster I diacylglycerol kinases is sufficient to target the proteins to cell membranes. Vaultier MN, et al. FEBS Lett, 2008 May 28. PMID 18466768
    3. Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development. Gómez-Merino FC, et al. J Biol Chem, 2005 Oct 14. PMID 16081412
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DGK1 and DGK2 from cluster I in Arabidopsis thaliana possess amino-terminal hydrophobic segments that are sufficient to address them to endoplasmic reticulum membranes.
      Title: The hydrophobic segment of Arabidopsis thaliana cluster I diacylglycerol kinases is sufficient to target the proteins to cell membranes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001342967.1
    NM_001342968.1
    NM_120874.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables ATP-dependent diacylglycerol kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    diacylglycerol kinase1
    NP_196409.1
    • diacylglycerol kinase1 (DGK1); FUNCTIONS IN: diacylglycerol kinase activity, calcium ion binding; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, intracellular signaling pathway; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase C-like, phorbol ester/diacylglycerol binding (InterPro:IPR002219), Diacylglycerol kinase, catalytic domain (InterPro:IPR001206), Diacylglycerol kinase, accessory domain (InterPro:IPR000756); BEST Arabidopsis thaliana protein match is: diacylglycerol kinase 2 (TAIR:AT5G63770.1); Has 2279 Blast hits to 1631 proteins in 306 species: Archae - 0; Bacteria - 350; Metazoa - 1446; Fungi - 0; Plants - 254; Viruses - 0; Other Eukaryotes - 229 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2524687..2529421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120874.3 → NP_196409.1  diacylglycerol kinase1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196409.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39017, Q9SD92
      UniProtKB/TrEMBL
      A0A178ULH8, A0A5S9Y2D2, A0A654FZ89
      Conserved Domains (4) summary
      smart00109
      Location:80 → 137
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00046
      Location:363 → 489
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      pfam00609
      Location:508 → 664
      DAGK_acc; Diacylglycerol kinase accessory domain
      cd20805
      Location:150 → 215
      C1_DGK_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the diacylglycerol kinase family

    2. NM_001342968.1 → NP_001331085.1  diacylglycerol kinase1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39017, Q9SD92
      UniProtKB/TrEMBL
      A0A178ULH8, A0A5S9Y2D2, A0A654FZ89
      Conserved Domains (4) summary
      smart00109
      Location:80 → 137
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00046
      Location:363 → 489
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      pfam00609
      Location:508 → 664
      DAGK_acc; Diacylglycerol kinase accessory domain
      cd20805
      Location:150 → 215
      C1_DGK_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the diacylglycerol kinase family

    3. NM_001342967.1 → NP_001331084.1  diacylglycerol kinase1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BCS4, A0A654FZ89
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39017.2

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