AnxB11 Annexin B11 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: AnxB11provided by FlyBase
Official Full Name: Annexin B11provided by FlyBase
Primary source: FLYBASE:FBgn0030749
Locus tag: Dmel_CG9968
See related: AllianceGenome:FB:FBgn0030749
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: annexin; Anxb11; ANXB11; Axb11; BcDNA:GH16395; CG9968; Dmel\CG9968
Summary: Predicted to enable calcium-dependent phospholipid binding activity; phosphatidylethanolamine binding activity; and phosphatidylserine binding activity. Predicted to be involved in response to calcium ion. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in several structures, including adult head; adult heart; dorsal epidermis primordium; embryonic anal pad; and gut section. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 23 and inclusion body myopathy and brain white matter abnormalities. Orthologous to human ANXA11 (annexin A11) and ANXA7 (annexin A7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (16416958..16422265, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (16310991..16316298, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-dependent phospholipid binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent phospholipid binding	ISS Inferred from Sequence or Structural Similarity more info
enables phosphatidylserine binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in response to calcium ion	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: AnxB11-PA; AnxB11-PB; AnxB11-PC; AnxB11-PD; AnxB11-PE; AnxB11-PF; AnxB11-PG; CG9968-PA; CG9968-PB; CG9968-PC; CG9968-PD; CG9968-PE; CG9968-PF; CG9968-PG