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    MMT methionine S-methyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835044, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MMT
    Official Full Name
    methionine S-methyltransferase
    Primary source
    TAIR:AT5G49810
    Locus tag
    AT5G49810
    See related
    Araport:AT5G49810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    methionine S-methyltransferase
    Summary
    Arabidopsis thaliana methionine S-methyltransferase, an enzyme that catalyzes S -methylmethionine formation.
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    Genomic context

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    See MMT in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (20239293..20246398)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Polyketide cyclase/dehydrase and lipid transport superfamily protein Neighboring gene root UVB sensitive protein (Protein of unknown function, DUF647) Neighboring gene exocyst complex component 84B Neighboring gene ATP-dependent Clp protease Neighboring gene Mannose-binding lectin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An essential role of s-adenosyl-L-methionine:L-methionine s-methyltransferase in selenium volatilization by plants. Methylation of selenomethionine to selenium-methyl-L-selenium- methionine, the precursor of volatile selenium. Tagmount A, et al. Plant Physiol, 2002 Oct. PMID 12376649, Free PMC Article
    2. Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio. Kocsis MG, et al. Plant Physiol, 2003 Apr. PMID 12692340, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_124359.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables methionine S-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within S-adenosylmethionine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within selenium compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    methionine S-methyltransferase
    NP_199792.1
    • methionine S-methyltransferase (MMT); CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Methyltransferase small (InterPro:IPR007848), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20239293..20246398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124359.4 → NP_199792.1  methionine S-methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199792.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LTB2, Q9SWR2
      UniProtKB/TrEMBL
      A0A5S9YCI6, A0A654GAI3
      Conserved Domains (1) summary
      PLN02672
      Location:1 → 1070
      PLN02672; methionine S-methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTB2.1

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