U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG4995 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34390, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG4995provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032219
    Locus tag
    Dmel_CG4995
    See related
    AllianceGenome:FB:FBgn0032219
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18626; Dmel\CG4995
    Summary
    Predicted to enable high-affinity L-arginine transmembrane transporter activity and high-affinity lysine transmembrane transporter activity. Predicted to be involved in mitochondrial L-ornithine transmembrane transport. Predicted to be active in mitochondrion. Is expressed in adult head. Orthologous to human SLC25A29 (solute carrier family 25 member 29). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG4995 in Genome Data Viewer
    Location:
    31D7-31D8; 2-41 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10322476..10324990)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10322476..10324990)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ubiquitin specific protease 14 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribonucleoside diphosphate reductase large subunit Neighboring gene Schwannomin interacting protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A novel Drosophila mitochondrial carrier protein acts as a Mg(2+) exporter in fine-tuning mitochondrial Mg(2+) homeostasis. Cui Y, et al. Biochim Biophys Acta, 2016 Jan. PMID 26462626
    2. Differential amino acid transporter expression in adult Drosophila melanogaster tissues. Wright Y, et al. MicroPubl Biol, 2024. PMID 38481556, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    5. Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila. Bossen J, et al. Int J Mol Sci, 2023 Mar 15. PMID 36982710, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables high-affinity L-arginine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables high-affinity lysine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG4995-PA
    CG4995-PB
    CG4995-PC
    CG4995-PD

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10322476..10324990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164914.2 → NP_723564.1  uncharacterized protein Dmel_CG4995, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723564.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IH44, Q9VKZ4, Q9VKZ5
      Related
      FBpp0079579
      Conserved Domains (2) summary
      PTZ00169
      Location:41 → 295
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:128 → 218
      Mito_carr; Mitochondrial carrier protein

    2. NM_135536.3 → NP_609380.1  uncharacterized protein Dmel_CG4995, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609380.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IH44, Q9VKZ4, Q9VKZ5
      Related
      FBpp0079580
      Conserved Domains (2) summary
      PTZ00169
      Location:41 → 295
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:128 → 218
      Mito_carr; Mitochondrial carrier protein

    3. NM_164915.2 → NP_723565.1  uncharacterized protein Dmel_CG4995, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723565.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q76NQ2, Q8IH44
      Related
      FBpp0079581
      Conserved Domains (2) summary
      PTZ00169
      Location:2 → 256
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:89 → 179
      Mito_carr; Mitochondrial carrier protein

    4. NM_001273396.1 → NP_001260325.1  uncharacterized protein Dmel_CG4995, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260325.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q76NQ2, Q8IH44
      Conserved Domains (2) summary
      PTZ00169
      Location:2 → 256
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:89 → 179
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q76NQ2 Q76NQ2
    Q8IH44 Q8IH44
    Q9VKZ5 Q9VKZ5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous