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    NEK3 NIMA-related kinase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832912, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NEK3
    Official Full Name
    NIMA-related kinase 3
    Primary source
    TAIR:AT5G28290
    Locus tag
    AT5G28290
    See related
    Araport:AT5G28290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNEK3; NIMA-related kinase 3; NIMA-RELATED KINASE3; T8M17.60; T8M17_60
    Summary
    Encodes AtNek3, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
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    Genomic context

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    See NEK3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Sequence:
    Chromosome: 5; NC_003076.8 (10278615..10282824, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Defensin-like (DEFL) family protein Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001344066.1
    NM_001344067.1
    NM_122712.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NIMA-related kinase 3
    NP_198181.1
    • NIMA-related kinase 3 (NEK3); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 2 (TAIR:AT3G04810.2); Has 124194 Blast hits to 122056 proteins in 3852 species: Archae - 107; Bacteria - 14304; Metazoa - 45560; Fungi - 12271; Plants - 30693; Viruses - 504; Other Eukaryotes - 20755 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      10278615..10282824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122712.3 → NP_198181.1  NIMA-related kinase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198181.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RX66
      UniProtKB/TrEMBL
      A0A178UI68, A0A5S9Y825
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    2. NM_001344066.1 → NP_001330383.1  NIMA-related kinase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RX66
      UniProtKB/TrEMBL
      A0A178UI68, A0A5S9Y825
      Conserved Domains (1) summary
      cd08215
      Location:3 → 258
      STKc_Nek; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase

    3. NM_001344067.1 → NP_001330382.1  NIMA-related kinase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAP6, A0A5S9Y825
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RX66.1

    Gene LinkOut

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