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    UGT75B1 UDP-glucosyltransferase 75B1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837058, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGT75B1
    Official Full Name
    UDP-glucosyltransferase 75B1
    Primary source
    TAIR:AT1G05560
    Locus tag
    AT1G05560
    See related
    Araport:AT1G05560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T25N20.21; UDP-GLUCOSE TRANSFERASE 1; UDP-GLUCOSYLTRANSFERASE; UDP-glucosyltransferase 75B1; UGT1
    Summary
    A UDP-glucose transferase localized in the phragmoplast. It has been co-purified with the callose synthase complex and may transfer UDP-glucose from sucrose synthase to the callose synthase and thus help form a substrate channel for the synthesis of callose at the forming cell plate. Induced by salicylic acid. Independent of NPR1 for their induction by salicylic acid. UGT1 encodes a protein with glucosyltransferase activity with high sequence homology to UGT2 (AT1G05530). It belongs to an UGT subfamily that binds UDP-glucose but not UDP-glucuronate, UDP-galactose, or UDP-rhamnose as the glycosyl donor. UGT1 was shown to be able to use abscisic acid as glycosylation substrate in the presence of UDP-glucose. UGT1/UGT75B1 catalyzes the formation of the p-aminobenzoate-glucose ester in vitro and in vivo. It appears to be the enzyme predominantly responsible for pABA-Glc formation in Arabidopsis based on assays in leaves, flowers, and siliques.
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    Genomic context

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    See UGT75B1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (1645300..1647435, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF295) Neighboring gene hypothetical protein (DUF295) Neighboring gene ncRNA Neighboring gene callose synthase 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis UDP-glycosyltransferase75B1, conjugates abscisic acid and affects plant response to abiotic stresses. Chen TT, et al. Plant Mol Biol, 2020 Mar. PMID 31894456
    2. Metabolism of the folate precursor p-aminobenzoate in plants: glucose ester formation and vacuolar storage. Eudes A, et al. J Biol Chem, 2008 May 30. PMID 18385129, Free PMC Article
    3. A novel UDP-glucose transferase is part of the callose synthase complex and interacts with phragmoplastin at the forming cell plate. Hong Z, et al. Plant Cell, 2001 Apr. PMID 11283335, Free PMC Article
    4. Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases. Gandia-Herrero F, et al. Plant J, 2008 Dec. PMID 18702669
    5. The plant glycosyltransferase clone collection for functional genomics. Lao J, et al. Plant J, 2014 Aug. PMID 24905498

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis UGT75B1 plays an important role in coping with abiotic stresses via glycosylation of abscisic acid
      Title: The Arabidopsis UDP-glycosyltransferase75B1, conjugates abscisic acid and affects plant response to abiotic stresses.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100435.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucose:4-aminobenzoate acylglucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glucosyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables UDP-glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables UDP-glycosyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables abscisic acid glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables indole-3-acetate beta-glucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within para-aminobenzoic acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in phragmoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glucosyltransferase 75B1
    NP_563742.1
    • UDP-glucosyltransferase 75B1 (UGT75B1); CONTAINS InterPro DOMAIN/s: UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-glucosyl transferase 75B2 (TAIR:AT1G05530.1); Has 7961 Blast hits to 7890 proteins in 509 species: Archae - 0; Bacteria - 579; Metazoa - 2125; Fungi - 39; Plants - 5043; Viruses - 112; Other Eukaryotes - 63 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1645300..1647435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331554.1 → NP_001320882.1  UDP-glucosyltransferase 75B1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AP70, A0A654E8G8
      Conserved Domains (1) summary
      PLN02152
      Location:51 → 502
      PLN02152; indole-3-acetate beta-glucosyltransferase

    2. NM_100435.3 → NP_563742.1  UDP-glucosyltransferase 75B1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563742.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LR44
      UniProtKB/TrEMBL
      A0A178WES5, A0A384LJH7, A0A654E8G8, W8QPC2
      Conserved Domains (1) summary
      PLN02152
      Location:1 → 452
      PLN02152; indole-3-acetate beta-glucosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LR44.1

    Gene LinkOut

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