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    ATBRXL2 DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820614, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATBRXL2
    Official Full Name
    DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein
    Primary source
    TAIR:AT3G14000
    Locus tag
    AT3G14000
    See related
    Araport:AT3G14000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BRX-LIKE2
    Summary
    Belongs to five-member BRX gene family. Arabidopsis BRX genes share high levels of similarity among each others, with several conserved domains. The most distinct is BRX domain - highly conserved in all BRX genes among distantly related species. This protein-protein interaction domain is required and sufficient for BRX activity.
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    Genomic context

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    See ATBRXL2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (4630865..4634081, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SKI/DACH domain protein Neighboring gene dentin sialophosphoprotein, putative (DUF1296) Neighboring gene CTC-interacting domain 4 Neighboring gene ncRNA Neighboring gene nuclear factor Y, subunit A6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tuning self-renewal in the Arabidopsis stomatal lineage by hormone and nutrient regulation of asymmetric cell division. Gong Y, et al. Elife, 2021 Mar 19. PMID 33739283, Free PMC Article
    2. Mapping and engineering of auxin-induced plasma membrane dissociation in BRX family proteins. Koh SWH, et al. Plant Cell, 2021 Jul 19. PMID 33751121, Free PMC Article
    3. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    4. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112254.3
    NM_202580.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in stomatal lineage progression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein
    NP_188016.2
    • ATBRXL2; CONTAINS InterPro DOMAIN/s: Disease resistance/zinc finger/chromosome condensation-like region (InterPro:IPR013591); BEST Arabidopsis thaliana protein match is: BREVIS RADIX-like 3 (TAIR:AT1G54180.2); Has 725 Blast hits to 435 proteins in 44 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 15; Plants - 701; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).
    NP_974309.1
    • ATBRXL2; CONTAINS InterPro DOMAIN/s: Disease resistance/zinc finger/chromosome condensation-like region (InterPro:IPR013591); BEST Arabidopsis thaliana protein match is: BREVIS RADIX-like 3 (TAIR:AT1G54180.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4630865..4634081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202580.2 → NP_974309.1  DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974309.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GYL9, Q9LVJ9, Q9LVK0
      UniProtKB/TrEMBL
      A0A178VEV0, A0A5S9XDC9, A0A7G2EKI2
      Conserved Domains (2) summary
      pfam08381
      Location:318 → 373
      BRX; Transcription factor regulating root and shoot growth via Pin3
      pfam13713
      Location:33 → 64
      BRX_N; Transcription factor BRX N-terminal domain

    2. NM_112254.3 → NP_188016.2  DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188016.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GYL9, Q9LVJ9, Q9LVK0
      UniProtKB/TrEMBL
      A0A178VEV0, A0A5S9XDC9, A0A7G2EKI2
      Conserved Domains (2) summary
      pfam08381
      Location:318 → 373
      BRX; Transcription factor regulating root and shoot growth via Pin3
      pfam13713
      Location:33 → 64
      BRX_N; Transcription factor BRX N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GYL9.1

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