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    Obp99a Odorant-binding protein 99a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43488, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp99aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 99aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039678
    Locus tag
    Dmel_CG18111
    See related
    AllianceGenome:FB:FBgn0039678
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    99a; BcDNA:RH70762; CG18111; DmelObp99a; Dmel\CG18111; obp99a; OBP99a; OBP99A
    Summary
    Predicted to enable odorant binding activity. Predicted to be involved in olfactory behavior; response to pheromone; and sensory perception of smell. Located in endomembrane system. Is expressed in several structures, including antennal anlage; antennal primordium; central brain anlage; central brain primordium; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Obp99a in Genome Data Viewer
    Location:
    99B7-99B7; 3-99 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29671657..29672334)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25497379..25498056)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pickpocket 20 Neighboring gene pickpocket 30 Neighboring gene pickpocket 19 Neighboring gene Bub3 Neighboring gene CAP-D2 condensin subunit Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural variation in odorant recognition among odorant-binding proteins in Drosophila melanogaster. Wang P, et al. Genetics, 2010 Mar. PMID 20026676, Free PMC Article
    2. The invertebrate odorant-binding protein LUSH is required for normal olfactory behavior in Drosophila. Kim MS, et al. Chem Senses, 2001 Feb. PMID 11238251
    3. Proteome profiling reveals tissue-specific protein expression in the male reproductive system of Drosophila melanogaster. Yamamoto MT, et al. Fly (Austin), 2010 Jan-Mar. PMID 20139713
    4. Conservation of the behavioral and transcriptional response to social experience among Drosophilids. Shultzaberger RK, et al. Genes Brain Behav, 2019 Jan. PMID 29797548, Free PMC Article
    5. Stochastic Modeling of Gene Expression Evolution Uncovers Tissue- and Sex-Specific Properties of Expression Evolution in the Drosophila Genus. Pal S, et al. J Comput Biol, 2023 Jan. PMID 36037023, Free PMC Article

    See all (73) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables odorant binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in olfactory behavior ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in response to pheromone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Odorant-binding protein 99a
    Names
    CG18111-PA
    CG18111-PB
    Obp99a-PA
    Obp99a-PB
    odorant binding protein 99a

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29671657..29672334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143450.3 → NP_651707.1  Odorant-binding protein 99a, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651707.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9QIH3, A9QII9, A9QIJ4, A9QIU5, Q9VAJ4
      UniProtKB/TrEMBL
      D1FYH5, D1FYI8, D1FYJ0, D1FYR1
      Related
      FBpp0084816
      Conserved Domains (1) summary
      smart00708
      Location:29 → 130
      PhBP; Insect pheromone/odorant binding protein domains

    2. NM_001300657.1 → NP_001287586.1  Odorant-binding protein 99a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287586.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9QIH3, A9QII9, A9QIJ4, A9QIU5, Q9VAJ4
      UniProtKB/TrEMBL
      D1FYH5, D1FYI8, D1FYJ0, D1FYR1
      Conserved Domains (1) summary
      smart00708
      Location:29 → 130
      PhBP; Insect pheromone/odorant binding protein domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D1FYH5 D1FYH5
    Q9VAJ4.2 Q9VAJ4

    Gene LinkOut

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