AO L-aspartate oxidase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: AO
Official Full Name: L-aspartate oxidase
Primary source: TAIR:AT5G14760
Locus tag: AT5G14760
See related: Araport:AT5G14760
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: FIN4; FLAGELLIN-INSENSITIVE 4; L-aspartate oxidase; T9L3.60; T9L3_60
Summary: At5g14760 encodes for L-aspartate oxidase involved in the early steps of NAD biosynthesis. In contrary to the EC 1.4.3.16 (l-aspartate oxidase - deaminating) the enzyme catalyzes the reaction L-aspartate + O2 = iminoaspartate (alpha-iminosuccinate) + H2O2
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_121480.4

Function	Evidence Code	Pubs
enables L-aspartate oxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NAD biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within NAD biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within NAD biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info

NP_568304.1

L-aspartate oxidase (AO); FUNCTIONS IN: electron carrier activity, oxidoreductase activity, L-aspartate oxidase activity; INVOLVED IN: NAD biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (InterPro:IPR015939), Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal (InterPro:IPR003953), Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal (InterPro:IPR004112), L-aspartate oxidase (InterPro:IPR005288); BEST Arabidopsis thaliana protein match is: succinate dehydrogenase 1-1 (TAIR:AT5G66760.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).