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    meru meru [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    meruprovided by FlyBase
    Official Full Name
    meruprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052150
    Locus tag
    Dmel_CG32150
    See related
    AllianceGenome:FB:FBgn0052150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12712; CG15714; CG32150; Dmel\CG32150
    Summary
    Involved in asymmetric cell division. Located in apical plasma membrane and posterior cell cortex. Is expressed in wing disc. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See meru in Genome Data Viewer
    Location:
    72A2-72A2; 3-43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15837773..15844062, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15830873..15837162, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-263b stem loop Neighboring gene pH-sensitive chloride channel 1 Neighboring gene long non-coding RNA:CR44051 Neighboring gene long non-coding RNA:CR44050

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lateral inhibition: Two modes of non-autonomous negative autoregulation by neuralized. Miller SW, et al. PLoS Genet, 2018 Jul. PMID 30028887, Free PMC Article
    2. Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division. Banerjee JJ, et al. Elife, 2017 Jun 30. PMID 28665270, Free PMC Article
    3. Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. Hilgers V, et al. PLoS Biol, 2010 Jun 15. PMID 20563308, Free PMC Article
    4. RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Sherwood V, et al. Mol Biol Cell, 2008 Apr. PMID 18272789, Free PMC Article
    5. Intronic miR-932 targets the coding region of its host gene, Drosophila neuroligin2. Qian J, et al. Exp Cell Res, 2016 Jun 10. PMID 26844630

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in asymmetric cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in posterior cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    meru
    Names
    CG32150-PA
    CG32150-PC
    CG32150-PD
    meru-PA
    meru-PC
    meru-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15837773..15844062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168635.3 → NP_730077.1  meru, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUU9
      Related
      FBpp0075290

    2. NM_001259851.3 → NP_001246780.1  meru, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246780.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NDS6

    3. NM_001259850.3 → NP_001246779.1  meru, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246779.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUU9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NDS6 M9NDS6
    Q9VUU9 Q9VUU9
    Q9VUV0 Q9VUV0

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