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    Camp Cathelicidin-like antimicrobial protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36948, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Campprovided by FlyBase
    Official Full Name
    Cathelicidin-like antimicrobial proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034210
    Locus tag
    Dmel_CG6568
    See related
    AllianceGenome:FB:FBgn0034210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg6568; CG6568; dCAMP; Dmel\CG6568
    Summary
    Involved in defense response to bacterium. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Camp in Genome Data Viewer
    Location:
    54B7-54B7; 2-82 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17405304..17407427, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13292809..13294932, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Alanine-TGC 2-1 Neighboring gene uncharacterized protein Neighboring gene Vajk4 Neighboring gene Proteasome alpha5 subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterisation of the Drosophila cg6568 gene in host defence against Mycobacterium marinum. Jin HS, et al. Microbes Infect, 2017 Jun. PMID 28245983
    2. Genomic changes under rapid evolution: selection for parasitoid resistance. Jalvingh KM, et al. Proc Biol Sci, 2014 Mar 22. PMID 24500162, Free PMC Article
    3. Systems genetics of complex traits in Drosophila melanogaster. Ayroles JF, et al. Nat Genet, 2009 Mar. PMID 19234471, Free PMC Article
    4. Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates. Olson JM, et al. G3 (Bethesda), 2019 Nov 5. PMID 31690598, Free PMC Article
    5. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. cg6568 was essential both for D. melanogaster survival and the exertion of antimicrobial effects during Mycobacterium marinum infection
      Title: Functional characterisation of the Drosophila cg6568 gene in host defence against Mycobacterium marinum.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cathelicidin-like antimicrobial protein
    Names
    CG6568-PA
    CG6568-PB
    Camp-PA
    Camp-PB
    cathelicidin-like antimicrobial protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17405304..17407427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137360.2 → NP_611204.2  Cathelicidin-like antimicrobial protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611204.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRA9, Q9V806
      Related
      FBpp0086119
      Conserved Domains (1) summary
      cl21562
      Location:341 → 378
      DDE_Tnp_4; DDE superfamily endonuclease

    2. NM_001299594.1 → NP_001286523.1  Cathelicidin-like antimicrobial protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286523.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGS5
      Conserved Domains (1) summary
      cl21562
      Location:273 → 310
      DDE_Tnp_4; DDE superfamily endonuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LGS5 A0A0B4LGS5
    Q8MRA9 Q8MRA9

    Gene LinkOut

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