U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Kaz-m1 Kazal-type protease inhibitor m1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43154, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Kaz-m1provided by FlyBase
    Official Full Name
    Kazal-type protease inhibitor m1provided by FlyBase
    Primary source
    FLYBASE:FBgn0002578
    Locus tag
    Dmel_CG8342
    See related
    AllianceGenome:FB:FBgn0002578
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE44854; CG8342; Dmel\CG8342; E(spl)-m1; E(spl)m1; HLHm1; lincRNA.856; m1
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Is expressed in several structures, including circulatory system primordium; embryonic/larval midgut primordium; gut section; procrystal cell; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Kaz-m1 in Genome Data Viewer
    Location:
    96F10-96F10; 3-89 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26014721..26016487)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21840443..21842209)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45039 Neighboring gene Enhancer of split malpha, Bearded family member Neighboring gene long non-coding RNA:CR45040 Neighboring gene Enhancer of split m2, Bearded family member Neighboring gene long non-coding RNA:CR43643

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster. Knust E, et al. EMBO J, 1987 Dec 20. PMID 16453817, Free PMC Article
    2. A functional analysis of the genes Enhancer of split and HLH-m5 during early neurogenesis in Drosophila melanogaster. Tietze K, et al. Rouxs Arch Dev Biol, 1993 Jan. PMID 28305975
    3. Neural hyperplasia induced by RNA interference with m4/malpha gene activity. Nagel AC, et al. Mech Dev, 2000 Nov. PMID 11044604
    4. Drosophila evolution challenges postulated redundancy in the E(spl) gene complex. Maier D, et al. Proc Natl Acad Sci U S A, 1993 Jun 15. PMID 8516287, Free PMC Article
    5. The Enhancer of split complex arose prior to the diversification of schizophoran flies and is strongly conserved between Drosophila and stalk-eyed flies (Diopsidae). Baker RH, et al. BMC Evol Biol, 2011 Dec 8. PMID 22151427, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Kazal-type protease inhibitor m1
    Names
    CG8342-PA
    CG8342-PB
    E(spl) region transcript m1
    Kaz-m1-PA
    Kaz-m1-PB
    Kazal-type protease inhibitor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26014721..26016487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276051.2 → NP_001262980.1  Kazal-type protease inhibitor m1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262980.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97176, Q56LL2, Q56LL5, Q56LP9, Q56LS4, Q56LS6, Q56LX2, Q56LX7, Q56LZ2, Q56LZ7, Q56M22, Q56M82, Q56MB6, Q56MB7, Q56MC4, Q56MH8, Q56MI0, Q56MI2, Q56MI3, Q56MJ1, Q5S421, Q5S481, Q5S4G5, Q5S4I9, Q5S4L3
      UniProtKB/TrEMBL
      A0A0B4KH50
      Conserved Domains (1) summary
      smart00280
      Location:29 → 67
      KAZAL; Kazal type serine protease inhibitors

    2. NM_079783.4 → NP_524507.1  Kazal-type protease inhibitor m1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524507.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97176, Q56LL2, Q56LL5, Q56LP9, Q56LS4, Q56LS6, Q56LX2, Q56LX7, Q56LZ2, Q56LZ7, Q56M22, Q56M82, Q56MB6, Q56MB7, Q56MC4, Q56MH8, Q56MI0, Q56MI2, Q56MI3, Q56MJ1, Q5S421, Q5S481, Q5S4G5, Q5S4I9, Q5S4L3
      UniProtKB/TrEMBL
      A0A0B4KH50
      Related
      FBpp0084331
      Conserved Domains (1) summary
      smart00280
      Location:29 → 67
      KAZAL; Kazal type serine protease inhibitors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KH50 A0A0B4KH50
    O97176.1 O97176
    Q56LZ6 Q56LZ6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools