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    CG6005 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42279, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6005provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038672
    Locus tag
    Dmel_CG6005
    See related
    AllianceGenome:FB:FBgn0038672
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6005
    Summary
    Predicted to enable phosphatidylinositol 3-kinase regulator activity. Involved in wound healing. Predicted to be active in early endosome membrane and late endosome membrane. Is expressed in organism. Orthologous to human WDR91 (WD repeat domain 91). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6005 in Genome Data Viewer
    Location:
    91E3-91E3; 3-65 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19022458..19024030, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14848180..14849752, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene small ribonucleoprotein particle U1 subunit C Neighboring gene GUK-holder Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glutamyl-tRNA amidotransferase, subunit A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in the Drosophila mitochondrial tRNA amidotransferase, bene/gatA, cause growth defects in mitotic and endoreplicating tissues. Morris JZ, et al. Genetics, 2008 Feb. PMID 18245325, Free PMC Article
    2. Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Campos I, et al. Genetics, 2010 Jan. PMID 19884309, Free PMC Article
    3. Genome-wide measurement of spatial expression in patterning mutants of Drosophila melanogaster. Combs PA, et al. F1000Res, 2017. PMID 28299188, Free PMC Article
    4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    5. Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing. Mazloomian A, et al. RNA Biol, 2015. PMID 26512413, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol 3-kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol 3-kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in early endosome to late endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in early endosome to late endosome transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in wound healing HMP PubMed 
    Component Evidence Code Pubs
    is_active_in early endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6005-PA
    CG6005-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19022458..19024030 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300471.1 → NP_001287400.1  uncharacterized protein Dmel_CG6005, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287400.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE12

    2. NM_142514.2 → NP_650771.1  uncharacterized protein Dmel_CG6005, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650771.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE12
      Related
      FBpp0083133
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VE12 Q9VE12

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