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    CG4554 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37570, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4554provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034734
    Locus tag
    Dmel_CG4554
    See related
    AllianceGenome:FB:FBgn0034734
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4554; GM01751p
    Summary
    Predicted to be part of 90S preribosome and small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP20 (UTP20 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4554 in Genome Data Viewer
    Location:
    58E3-58E3; 2-100 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22483303..22492033)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18370808..18379538)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene plexus Neighboring gene gasoline

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rare variants in MYH15 modify amyotrophic lateral sclerosis risk. Kim H, et al. Hum Mol Genet, 2019 Jul 15. PMID 30985904, Free PMC Article
    2. A neurogenetic mechanism of experience-dependent suppression of aggression. Ishii K, et al. Sci Adv, 2022 Sep 9. PMID 36070378, Free PMC Article
    3. Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster. Parker GA, et al. G3 (Bethesda), 2020 Mar 5. PMID 31969430, Free PMC Article
    4. Functional genomics identifies TOR-regulated genes that control growth and division. Guertin DA, et al. Curr Biol, 2006 May 23. PMID 16713952
    5. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4554-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22483303..22492033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137832.2 → NP_611676.1  uncharacterized protein Dmel_CG4554 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611676.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W246
      Related
      FBpp0071744
      Conserved Domains (1) summary
      pfam07539
      Location:840 → 1444
      DRIM; Down-regulated in metastasis
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3N8 Q8T3N8
    Q9W246 Q9W246

    Gene LinkOut

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