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    Ag5r Antigen 5-related [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44631, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ag5rprovided by FlyBase
    Official Full Name
    Antigen 5-relatedprovided by FlyBase
    Primary source
    FLYBASE:FBgn0015010
    Locus tag
    Dmel_CG9538
    See related
    AllianceGenome:FB:FBgn0015010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    agr; Agr; Agr5; anon-WO0140519.74; CG9538; Dmel\CG9538
    Summary
    Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human R3HDML (R3H domain containing like) and PI15 (peptidase inhibitor 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ag5r in Genome Data Viewer
    Location:
    12F4-12F4; 1-49 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14784664..14786551, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14678697..14680584, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45522 Neighboring gene Antigen 5-related 2 Neighboring gene rutabaga Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel cDNA from Drosophila encoding a protein with similarity to mammalian cysteine-rich secretory proteins, wasp venom antigen 5, and plant group 1 pathogenesis-related proteins. Schreiber MC, et al. Gene, 1997 Jun 3. PMID 9218711
    2. Structure and expression of the antigen 5-related gene of Drosophila melanogaster. Kovalick GE, et al. Insect Biochem Mol Biol, 1998 Jul. PMID 9718681
    3. Sequence and expression of Drosophila Antigen 5-related 2, a new member of the CAP gene family. Megraw T, et al. Gene, 1998 Nov 19. PMID 9831665
    4. Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase. Radyuk SN, et al. Mech Ageing Dev, 2012 Jun. PMID 22579812
    5. Characterization of the SCP/TAPS gene family in Drosophila melanogaster. Kovalick GE, et al. Insect Biochem Mol Biol, 2005 Aug. PMID 15944079

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in multicellular organismal reproductive process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    antigen 5-related
    Names
    Ag5r-PA
    Ag5r-PB
    Ag5r-PC
    CG9538-PA
    CG9538-PB
    CG9538-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14784664..14786551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272618.1 → NP_001259547.1  antigen 5-related, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259547.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44425, Q9VY18
      Conserved Domains (1) summary
      cd05380
      Location:59 → 211
      SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...

    2. NM_001258742.2 → NP_001245671.1  antigen 5-related, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245671.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44425, Q9VY18
      Conserved Domains (1) summary
      cd05380
      Location:59 → 211
      SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...

    3. NM_080031.3 → NP_524770.1  antigen 5-related, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524770.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44425, Q9VY18
      Related
      FBpp0073754
      Conserved Domains (1) summary
      cd05380
      Location:59 → 211
      SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O44425 O44425
    Q24234 Q24234
    Q9VY18 Q9VY18

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