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    TotX Turandot X [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117460, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TotXprovided by FlyBase
    Official Full Name
    Turandot Xprovided by FlyBase
    Primary source
    FLYBASE:FBgn0044810
    Locus tag
    Dmel_CG31193
    See related
    AllianceGenome:FB:FBgn0044810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31193; Dmel\CG31193; tot; Tot X; totX; Totx; TOTX
    Summary
    Involved in cellular response to heat; cellular response to oxidative stress; and response to bacterium. Predicted to be located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TotX in Genome Data Viewer
    Location:
    93A3-93A3; 3-69 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20904917..20905518, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16730639..16731240, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44947 Neighboring gene Kctd12-like Neighboring gene grik Neighboring gene ncRNA Neighboring gene antisense RNA:CR44106 Neighboring gene uncharacterized protein Neighboring gene hadley

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parallel gene expression evolution in natural and laboratory evolved populations. Hsu SK, et al. Mol Ecol, 2021 Feb. PMID 32979867, Free PMC Article
    2. A functional study of the role of Turandot genes in Drosophila melanogaster: An emerging candidate mechanism for inducible heat tolerance. Amstrup AB, et al. J Insect Physiol, 2022 Nov-Dec. PMID 36396076
    3. Exploring cross-protective effects between cold and immune stress in Drosophila melanogaster. Wiil J, et al. Parasite, 2023. PMID 38084935, Free PMC Article
    4. Age and Diet Affect Genetically Separable Secondary Injuries that Cause Acute Mortality Following Traumatic Brain Injury in Drosophila. Katzenberger RJ, et al. G3 (Bethesda), 2016 Dec 7. PMID 27754853, Free PMC Article
    5. Trans-regulatory changes underpin the evolution of the Drosophila immune response. Ding SD, et al. PLoS Genet, 2022 Nov. PMID 36342922, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to oxidative stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    turandot X
    Names
    CG31193-PA
    TotX-PA
    turandot

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      20904917..20905518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080520.3 → NP_536781.2  turandot X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_536781.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN41, Q962D6
      UniProtKB/TrEMBL
      A0A1B2AKM5
      Related
      FBpp0083389
      Conserved Domains (1) summary
      pfam07240
      Location:45 → 125
      Turandot; Stress-inducible humoral factor Turandot
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IN41.1 Q8IN41

    Gene LinkOut

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