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    CG12517 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34506, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12517provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032311
    Locus tag
    Dmel_CG12517
    See related
    AllianceGenome:FB:FBgn0032311
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12517; Gbp4
    Summary
    Predicted to enable cytokine activity. Involved in chorion-containing eggshell formation. Predicted to be located in egg chorion. Is expressed in adult fat body. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12517 in Genome Data Viewer
    Location:
    32B3-32B3; 2-43 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10870167..10870722)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10870167..10870722)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Signal transducing adaptor molecule Neighboring gene long non-coding RNA:CR43807 Neighboring gene long non-coding RNA:CR45453 Neighboring gene long non-coding RNA:CR45454

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characteristics common to a cytokine family spanning five orders of insects. Matsumoto H, et al. Insect Biochem Mol Biol, 2012 Jun. PMID 22465148
    2. Proteolytic activation of Growth-blocking peptides triggers calcium responses through the GPCR Mthl10 during epithelial wound detection. O'Connor JT, et al. Dev Cell, 2021 Aug 9. PMID 34273275, Free PMC Article
    3. Drosophila growth-blocking peptide-like factor mediates acute immune reactions during infectious and non-infectious stress. Tsuzuki S, et al. Sci Rep, 2012. PMID 22355724, Free PMC Article
    4. Drosophila eggshell production: identification of new genes and coordination by Pxt. Tootle TL, et al. PLoS One, 2011. PMID 21637834, Free PMC Article
    5. Genome-wide mapping of in vivo targets of the Drosophila transcription factor Kruppel. Matyash A, et al. J Biol Chem, 2004 Jul 16. PMID 15131112

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cytokine activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chorion-containing eggshell formation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in egg chorion IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12517-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10870167..10870722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135621.2 → NP_609465.1  uncharacterized protein Dmel_CG12517 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609465.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMV4, Q9VKN6
      Related
      FBpp0079733
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKN6 Q9VKN6

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