U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    stg1 stargazin-like protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318064, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    stg1provided by FlyBase
    Official Full Name
    stargazin-like proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0288700
    Locus tag
    Dmel_CG46498
    See related
    AllianceGenome:FB:FBgn0288700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10985; CG11566; CG11568; CG11569; CG32514; CG32514-ORFA; CG33670; CG46498; Dmel\CG46498; Dro STG1; Stg1; STG1
    Old locus tag
    Dmel_CG11566; Dmel_CG33670
    Summary
    Enables channel regulator activity and neurotransmitter receptor regulator activity. Involved in regulation of glutamatergic synaptic transmission. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See stg1 in Genome Data Viewer
    Location:
    19F1-19F1; 1-65 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21093844..21111417)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20964871..20982444)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Catalytic subunit 3A of the oligosaccharyltransferase complex Neighboring gene bves Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44374 Neighboring gene uncoordinated Neighboring gene uncharacterized protein Neighboring gene lipid droplet defective

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Reconstitution of invertebrate glutamate receptor function depends on stargazin-like proteins. Walker CS, et al. Proc Natl Acad Sci U S A, 2006 Jul 11. PMID 16818877, Free PMC Article
    2. The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation. Kiragasi B, et al. Proc Natl Acad Sci U S A, 2020 Oct 13. PMID 32973097, Free PMC Article
    3. Novel Functional Properties of Drosophila CNS Glutamate Receptors. Li Y, et al. Neuron, 2016 Dec 7. PMID 27889096, Free PMC Article
    4. Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein. Ashraf NS, et al. Neurobiol Dis, 2020 Apr. PMID 31783119, Free PMC Article
    5. Identification and investigation of Drosophila postsynaptic density homologs. Liebl FL, et al. Bioinform Biol Insights, 2008 Nov 3. PMID 19812789, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    mobile_element

    • Loc: 21096195-21096861 mobile_element_type = transposon:S{}195
    • Loc: 21099849-21100262 mobile_element_type = transposon:INE-1{}6024

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables channel regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables neurotransmitter receptor regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of synaptic transmission, glutamatergic IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    stargazin-like protein
    Names
    CG46498-PC
    stargazin
    stargazin-like
    stg1-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21093844..21111417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001414114.1 → NP_001400987.1  stargazin-like protein [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2MGK8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JUQ5 Q7JUQ5
    Q9VRE6 Q9VRE6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools