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    CG15602 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32533, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15602provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030694
    Locus tag
    Dmel_CG15602
    See related
    AllianceGenome:FB:FBgn0030694
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15602
    Summary
    Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in abscission and mitotic cytokinesis checkpoint signaling. Predicted to be active in centrosome; cleavage furrow; and midbody. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human ZFYVE19 (zinc finger FYVE-type containing 19). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15602 in Genome Data Viewer
    Location:
    13F1-13F1; 1-52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15799426..15800961)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15693459..15694994)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene suppression of retinal degeneration disease 1 upon overexpression 2 Neighboring gene Peptidoglycan recognition protein LE Neighboring gene long non-coding RNA:CR44384 Neighboring gene scalloped

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MSL2 combines sensor and effector functions in homeostatic control of the Drosophila dosage compensation machinery. Villa R, et al. Mol Cell, 2012 Nov 30. PMID 23084834
    2. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Chen S, et al. Cell Rep, 2012 Feb 23. PMID 22832161, Free PMC Article
    3. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
    4. The Drosophila Helicase Maleless (MLE) is Implicated in Functions Distinct From its Role in Dosage Compensation. Cugusi S, et al. Mol Cell Proteomics, 2015 Jun. PMID 25776889, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol-3-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in abscission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cleavage furrow IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15602-PA
    CG15602-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15799426..15800961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298369.1 → NP_001285298.1  uncharacterized protein Dmel_CG15602, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285298.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ70, Q9VXP0
      Conserved Domains (1) summary
      cl22851
      Location:2 → 52
      PHD_SF; PHD finger superfamily

    2. NM_132849.3 → NP_573077.2  uncharacterized protein Dmel_CG15602, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573077.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ70, Q9VXP0
      Conserved Domains (1) summary
      cl22851
      Location:2 → 52
      PHD_SF; PHD finger superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QQ70 Q4QQ70

    Gene LinkOut

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