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    CG2247 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32111, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2247provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030320
    Locus tag
    Dmel_CG2247
    See related
    AllianceGenome:FB:FBgn0030320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2247; FBXL5
    Summary
    Involved in defense response to bacterium. Located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2247 in Genome Data Viewer
    Location:
    10C10-10D1; 1-35 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11606290..11611652, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11500323..11505685, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene rhomboid-4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Replication protein A3 Neighboring gene Methoprene-tolerant

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. How Many Parameters Does It Take to Describe Disease Tolerance? Louie A, et al. PLoS Biol, 2016 Apr. PMID 27088212, Free PMC Article
    2. Cis-regulatory variation is typically polyallelic in Drosophila. Gruber JD, et al. Genetics, 2009 Feb. PMID 19064705, Free PMC Article
    3. Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Ayres JS, et al. Genetics, 2008 Mar. PMID 18245331, Free PMC Article
    4. The Integrator complex cleaves nascent mRNAs to attenuate transcription. Tatomer DC, et al. Genes Dev, 2019 Nov 1. PMID 31530651, Free PMC Article
    5. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Barbosa P, et al. J Cell Biol, 2021 Feb 1. PMID 33382409, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2247-PA
    CG2247-PB
    CG2247-PC
    CG2247-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11606290..11611652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132507.2 → NP_572735.1  uncharacterized protein Dmel_CG2247, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572735.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYW5
      Related
      FBpp0073381
      Conserved Domains (1) summary
      pfam12937
      Location:647 → 686
      F-box-like; F-box-like

    2. NM_001258697.2 → NP_001245626.1  uncharacterized protein Dmel_CG2247, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NED4
      Conserved Domains (1) summary
      pfam12937
      Location:543 → 582
      F-box-like; F-box-like

    3. NM_001258698.2 → NP_001245627.1  uncharacterized protein Dmel_CG2247, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245627.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NF18
      Conserved Domains (1) summary
      pfam12937
      Location:646 → 685
      F-box-like; F-box-like

    4. NM_001258696.2 → NP_001245625.1  uncharacterized protein Dmel_CG2247, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245625.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYW5
      Conserved Domains (1) summary
      pfam12937
      Location:647 → 686
      F-box-like; F-box-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NED4 M9NED4
    M9NF18 M9NF18
    Q9VYW5 Q9VYW5

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